Comment on Ambra et al. Could Selenium Supplementation Prevent COVID-19? A Comprehensive Review of Available Studies. Molecules 2023, 28, 4130
Conflicts of Interest
References
- Ambra, R.; Melloni, S.; Venneria, E. Could Selenium Supplementation Prevent COVID-19? A Comprehensive Review of Available Studies. Molecules 2023, 28, 4130. [Google Scholar] [CrossRef] [PubMed]
- Zhang, J.; Taylor, E.W.; Bennett, K.; Saad, R.; Rayman, M.P. Association between regional selenium status and reported outcome of COVID-19 cases in China. Am. J. Clin. Nutr. 2020, 111, 1297–1299. [Google Scholar] [CrossRef] [PubMed]
- Du Laing, G.; Petrovic, M.; Lachat, C.; De Boevre, M.; Klingenberg, G.J.; Sun, Q.; De Saeger, S.; De Clercq, J.; Ide, L.; Vandekerckhove, L.; et al. Course and Survival of COVID-19 Patients with Comorbidities in Relation to the Trace Element Status at Hospital Admission. Nutrients 2021, 13, 3304. [Google Scholar] [CrossRef] [PubMed]
- Demircan, K.; Chillon, T.S.; Bracken, T.; Bulgarelli, I.; Campi, I.; Du Laing, G.; Fafi-Kremer, S.; Fugazzola, L.; Garcia, A.A.; Heller, R.; et al. Association of COVID-19 mortality with serum selenium, zinc and copper: Six observational studies across Europe. Front. Immunol. 2022, 13, 1022673. [Google Scholar] [CrossRef] [PubMed]
- Larvie, D.Y.; Perrin, M.T.; Donati, G.L.; Armah, S.M. COVID-19 Severity Is Associated with Selenium Intake among Young Adults with Low Selenium and Zinc Intake in North Carolina. Curr. Dev. Nutr. 2023, 7, 100044. [Google Scholar] [CrossRef] [PubMed]
- Li, S.; Banuelos, G.S.; Wu, L.; Shi, W. The changing selenium nutritional status of Chinese residents. Nutrients 2014, 6, 1103–1114. [Google Scholar] [CrossRef] [PubMed]
- Liu, Q.; Zhao, X.; Ma, J.; Mu, Y.; Wang, Y.; Yang, S.; Wu, Y.; Wu, F.; Zhou, Y. Selenium (Se) plays a key role in the biological effects of some viruses: Implications for COVID-19. Environ. Res. 2021, 196, 110984. [Google Scholar] [CrossRef] [PubMed]
- Wang, Y.; Huang, J.; Sun, Y.; Stubbs, D.; He, J.; Li, W.; Wang, F.; Liu, Z.; Ruzicka, J.A.; Taylor, E.W.; et al. SARS-CoV-2 suppresses mRNA expression of selenoproteins associated with ferroptosis, endoplasmic reticulum stress and DNA synthesis. Food Chem. Toxicol. 2021, 153, 112286. [Google Scholar] [CrossRef] [PubMed]
- Gallardo, I.A.; Todd, D.A.; Lima, S.T.; Chekan, J.R.; Chiu, N.H.; Taylor, E.W. SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles. Antioxidants 2023, 12, 559. [Google Scholar] [CrossRef] [PubMed]
- Moghaddam, A.; Heller, R.A.; Sun, Q.; Seelig, J.; Cherkezov, A.; Seibert, L.; Hackler, J.; Seemann, P.; Diegmann, J.; Pilz, M.; et al. Selenium Deficiency Is Associated with Mortality Risk from COVID-19. Nutrients 2020, 12, 2098. [Google Scholar] [CrossRef] [PubMed]
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Rayman, M.P.; Schomburg, L.; Zhang, J.; Taylor, E.W.; Du Laing, G.; Beck, M.; Hughes, D.J.; Heller, R. Comment on Ambra et al. Could Selenium Supplementation Prevent COVID-19? A Comprehensive Review of Available Studies. Molecules 2023, 28, 4130. Molecules 2024, 29, 2466. https://doi.org/10.3390/molecules29112466
Rayman MP, Schomburg L, Zhang J, Taylor EW, Du Laing G, Beck M, Hughes DJ, Heller R. Comment on Ambra et al. Could Selenium Supplementation Prevent COVID-19? A Comprehensive Review of Available Studies. Molecules 2023, 28, 4130. Molecules. 2024; 29(11):2466. https://doi.org/10.3390/molecules29112466
Chicago/Turabian StyleRayman, Margaret P., Lutz Schomburg, **song Zhang, Ethan Will Taylor, Gijs Du Laing, Melinda Beck, David J. Hughes, and Raban Heller. 2024. "Comment on Ambra et al. Could Selenium Supplementation Prevent COVID-19? A Comprehensive Review of Available Studies. Molecules 2023, 28, 4130" Molecules 29, no. 11: 2466. https://doi.org/10.3390/molecules29112466