A Bioactive Degradable Composite Bone Cement Based on Calcium Sulfate and Magnesium Polyphosphate
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
2.2. Preparation and Optimizing of CS/MPP/C3S Composite Bone Cement
2.3. Characterization of CS/MPP/C3S Composite Bone Cement
2.4. Degradation In Vitro
2.5. Cytocompatibility
2.6. Osteogenic Differentiation
2.7. Statistical Methods
3. Results and Discussion
3.1. Optimization of Bone Cement Components
3.2. Characterization and Properties of Bone Cement
3.3. Degradation of Bone Cement In Vitro
3.4. Cytotoxicity and Osteogenic Differentiation In Vitro
3.5. Osteogenic Differentiation
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Genes | ID | Direction | Sequences |
---|---|---|---|
β-Actin | 11461 | FORWARD | GTGCTATGTTGCTCTAGACTTCG |
REVERSE | ATGCCACAGGATTCCATACC | ||
runx2 | 12393 | FORWARD | ATGGCGTCAAACAGCCTCTTC |
REVERSE | TGGTGCTCGGATCCCAAAAG | ||
BMP2 | 12156 | FORWARD | TCTTCCGGGAACAGATACAGG |
REVERSE | TGGTGTCCAATAGTCTGGTCA | ||
OCN | 12096 | FORWARD | AAGACCGCCTACAAACGCATCTAT |
REVERSE | GCACTTCCTCATCTGAACTTTATTTTG | ||
OPN | 20750 | FORWARD | TTGGTGACTTGGTGGTGATCTAGT |
REVERSE | TCTCCTCTGAGCTGCCAGAATC | ||
COL1 | 12842 | FORWARD | TAAGGGTCCCCAATGGTGAGA |
REVERSE | GGGTCCCTCGACTCCTACAT |
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Peng, S.; Yang, X.; Zou, W.; Chen, X.; Deng, H.; Zhang, Q.; Yan, Y. A Bioactive Degradable Composite Bone Cement Based on Calcium Sulfate and Magnesium Polyphosphate. Materials 2024, 17, 1861. https://doi.org/10.3390/ma17081861
Peng S, Yang X, Zou W, Chen X, Deng H, Zhang Q, Yan Y. A Bioactive Degradable Composite Bone Cement Based on Calcium Sulfate and Magnesium Polyphosphate. Materials. 2024; 17(8):1861. https://doi.org/10.3390/ma17081861
Chicago/Turabian StylePeng, Su**, **nyue Yang, Wangcai Zou, **aolu Chen, Hao Deng, Qiyi Zhang, and Yonggang Yan. 2024. "A Bioactive Degradable Composite Bone Cement Based on Calcium Sulfate and Magnesium Polyphosphate" Materials 17, no. 8: 1861. https://doi.org/10.3390/ma17081861