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Case Report

Coexistence of Behçet’s Disease with Ankylosing Spondylitis and Familial Mediterranean Fever: A Rare Occurrence

by
Makram Frigui
1,*,
Manel Kechaou
1,
Moez Jallouli
1,
Neila Kaddour
1,
Habiba Bouhamed Chaabouni
2 and
Zouhir Bahloul
1
1
Department of Internal Medicine, Hedi Chaker Hospital, 3029 Sfax, Tunisia
2
Laboratory of Human Genetics, Tunis Medicine College, Tunis, Tunisia
*
Author to whom correspondence should be addressed.
Clin. Pract. 2011, 1(2), e34; https://doi.org/10.4081/cp.2011.e34
Submission received: 24 March 2011 / Revised: 24 March 2011 / Accepted: 29 April 2011 / Published: 6 May 2011

Abstract

Behçet's disease (BD) and familial Mediterranean fever (FMF), which are two separate diseases sharing some clinical features, may also coexist in the same patient. Further investigations are needed to understand whether this coexistence is due to either chance or geographical distribution patterns of these diseases or to common etiopathogenetic characteristics. Spondylarthritis as part of the clinical picture in these two diseases has been questioned and probably it is not a prominent characteristic of any of them. We report a 35- year-old Tunisian man who had an association of BD, FMF and Human Leukocyte Antigen (HLA) B27 positive ankylosing spondylitis. Although that spondylarthritis is an infrequent joint involvement of FMF and BD, it must be looked for in case of association of these diseases.
Keywords: Behçet’s disease; familial Mediterranean fever; ankylosing spondylitis; MEFV gene Behçet’s disease; familial Mediterranean fever; ankylosing spondylitis; MEFV gene

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MDPI and ACS Style

Frigui, M.; Kechaou, M.; Jallouli, M.; Kaddour, N.; Chaabouni, H.B.; Bahloul, Z. Coexistence of Behçet’s Disease with Ankylosing Spondylitis and Familial Mediterranean Fever: A Rare Occurrence. Clin. Pract. 2011, 1, e34. https://doi.org/10.4081/cp.2011.e34

AMA Style

Frigui M, Kechaou M, Jallouli M, Kaddour N, Chaabouni HB, Bahloul Z. Coexistence of Behçet’s Disease with Ankylosing Spondylitis and Familial Mediterranean Fever: A Rare Occurrence. Clinics and Practice. 2011; 1(2):e34. https://doi.org/10.4081/cp.2011.e34

Chicago/Turabian Style

Frigui, Makram, Manel Kechaou, Moez Jallouli, Neila Kaddour, Habiba Bouhamed Chaabouni, and Zouhir Bahloul. 2011. "Coexistence of Behçet’s Disease with Ankylosing Spondylitis and Familial Mediterranean Fever: A Rare Occurrence" Clinics and Practice 1, no. 2: e34. https://doi.org/10.4081/cp.2011.e34

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