Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease
Abstract
:1. Introduction
2. Materials and Methods
2.1. Animals
2.2. Tissue Collection
2.3. LA ICP-MS Imaging
2.4. Image Analysis
2.5. Statistical Analysis
3. Results
3.1. Copper (Cu)
3.2. Iron (Fe)
3.3. Zinc (Zn)
4. Discussion
4.1. Copper
4.2. Iron
4.3. Zinc
4.4. Limitations
4.5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Hosseinpour Mashkani, S.M.; Bishop, D.P.; Raoufi-Rad, N.; Adlard, P.A.; Shimoni, O.; Golzan, S.M. Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease. Cells 2023, 12, 1144. https://doi.org/10.3390/cells12081144
Hosseinpour Mashkani SM, Bishop DP, Raoufi-Rad N, Adlard PA, Shimoni O, Golzan SM. Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease. Cells. 2023; 12(8):1144. https://doi.org/10.3390/cells12081144
Chicago/Turabian StyleHosseinpour Mashkani, Seyed Mostafa, David P. Bishop, Newsha Raoufi-Rad, Paul A. Adlard, Olga Shimoni, and S. Mojtaba Golzan. 2023. "Distribution of Copper, Iron, and Zinc in the Retina, Hippocampus, and Cortex of the Transgenic APP/PS1 Mouse Model of Alzheimer’s Disease" Cells 12, no. 8: 1144. https://doi.org/10.3390/cells12081144