Characteristics of Fluorescent Intraoperative Dyes Helpful in Gross Total Resection of High-Grade Gliomas—A Systematic Review
Abstract
:1. Introduction
2. Materials and Methods
3. Results
3.1. 5-Aminolevulinic Acid (5-ALA)
3.2. Fluorescein
3.3. Indocyanine Green (ICG)
4. Discussion
4.1. 5-Aminolevulinic Acid (5-ALA)
4.2. Fluorescein
4.3. Indocyanine Green (ICG)
5. Limitations
6. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
- Chapter 5.16. World Cancer Report 2014; World Health Organization: Geneva, Switzerland, 2014; ISBN 978-9283204299.
- Porter, K.R.; McCarthy, B.J.; Berbaum, M.L.; Davis, F.G. Conditional Survival of All Primary Brain Tumor Patients by Age, Behavior, and Histology. Neuroepidemiology 2011, 36, 230–239. [Google Scholar] [CrossRef] [PubMed]
- Visser, O.; Ardanaz, E.; Botta, L.; Sant, M.; Tavilla, A.; Minicozzi, P.; Hackl, M.; Zielonke, N.; Oberaigner, W.; Van Eycken, E.; et al. Survival of adults with primary malignant brain tumours in Europe; Results of the EUROCARE-5 study. Eur. J. Cancer 2015, 51, 2231–2241. [Google Scholar] [CrossRef] [PubMed]
- Mazurek, M.; Litak, J.; Kamieniak, P.; Kulesza, B.; Jonak, K.E.; Baj, J.; Grochowski, C. Metformin as Potential Therapy for High-Grade Glioma. Cancers 2020, 12, 210. [Google Scholar] [CrossRef]
- Stupp, R.; Mason, W.P.; van den Bent, M.J.; Weller, M.; Fisher, B.; Taphoorn, M.J.B.; Belanger, K.; Brandes, A.A.; Marosi, C.; Bogdahn, U.; et al. Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma. N. Engl. J. Med. 2005, 352, 987–996. [Google Scholar] [CrossRef] [PubMed]
- Aldape, K.; Brindle, K.M.; Chesler, L.; Chopra, R.; Gajjar, A.; Gilbert, M.R.; Gottardo, N.; Gutmann, D.H.; Hargrave, D.; Holland, E.C.; et al. Challenges to curing primary brain tumours. Nat. Rev. Clin. Oncol. 2019, 16, 509–520. [Google Scholar] [CrossRef] [PubMed]
- Mazurek, M.; Grochowski, C.; Litak, J.; Osuchowska, I.; Maciejewski, R.; Kamieniak, P. Recent Trends of microRNA Significance in Pediatric Population Glioblastoma and Current Knowledge of Micro RNA Function in Glioblastoma Multiforme. Int. J. Mol. Sci. 2020, 21, 3046. [Google Scholar] [CrossRef]
- D’Alessio, A.; Proietti, G.; Sica, G.; Scicchitano, B.M. Pathological and Molecular Features of Glioblastoma and Its Peritumoral Tissue. Cancers 2019, 11, 469. [Google Scholar] [CrossRef]
- Lara-Velazquez, M.; Al-Kharboosh, R.; Jeanneret, S.; Vazquez-Ramos, C.; Mahato, D.; Tavanaiepour, D.; Rahmathulla, G.; Quinones-Hinojosa, A. Advances in Brain Tumor Surgery for Glioblastoma in Adults. Brain Sci. 2017, 7, 166. [Google Scholar] [CrossRef]
- Akimoto, J. Photodynamic Therapy for Malignant Brain Tumors. Neurol. Med.-Chir. 2016, 56, 151–157. [Google Scholar] [CrossRef]
- Castano, A.P.; Demidova, T.N.; Hamblin, M.R. Mechanisms in photodynamic therapy: Part two—cellular signaling, cell metabolism and modes of cell death. Photodiagnosis Photodyn. Ther. 2005, 2, 1–23. [Google Scholar] [CrossRef]
- Lee, J.Y.K.; Sheikh, S.; ** during 5-ALA–guided resections of glioblastomas adjacent to motor eloquent areas: Evaluation of resection rates and neurological outcome. Neurosurg. Focus 2014, 37, E16. [Google Scholar] [CrossRef]
- Eyüpoglu, I.Y.; Hore, N.; Merkel, A.; Buslei, R.; Buchfelder, M.; Savaskan, N. Supra-complete surgery via dual intraoperative visualization approach (DiVA) prolongs patient survival in glioblastoma. Oncotarget 2016, 7, 25755–25768. [Google Scholar] [CrossRef]
- Della Pepa, G.M.; Ius, T.; Menna, G.; La Rocca, G.; Battistella, C.; Rapisarda, A.; Mazzucchi, E.; Pignotti, F.; Alexandre, A.; Marchese, E.; et al. “Dark corridors” in 5-ALA resection of high-grade gliomas: Combining fluorescence-guided surgery and contrast-enhanced ultrasonography to better explore the surgical field. J. Neurosurg. Sci. 2019, 63, 688–696. [Google Scholar] [CrossRef]
- Della Pepa, G.M.; Ius, T.; La Rocca, G.; Gaudino, S.; Isola, M.; Pignotti, F.; Rapisarda, A.; Mazzucchi, E.; Giordano, C.; Dragonetti, V.; et al. 5-Aminolevulinic Acid and Contrast-Enhanced Ultrasound: The Combination of the Two Techniques to Optimize the Extent of Resection in Glioblastoma Surgery. Neuropathology 2020, 86, E529–E540. [Google Scholar] [CrossRef]
- Higuchi, T.; Yamaguchi, F.; Asakura, T.; Yoshida, D.; Oishi, Y.; Morita, A. Ultrasound modulates fluorescence strength and ABCG2 mRNA response to aminolevulinic acid in glioma cells. J. Nippon. Med. Sch. 2020. [Google Scholar] [CrossRef] [PubMed]
- Goryaynov, S.A.; Widhalm, G.; Goldberg, M.F.; Chelushkin, D.; Spallone, A.; Chernyshov, K.A.; Ryzhova, M.; Pavlova, G.; Revischin, A.; Shishkina, L.; et al. The Role of 5-ALA in Low-Grade Gliomas and the Influence of Antiepileptic Drugs on Intraoperative Fluorescence. Front. Oncol. 2019, 9, 423. [Google Scholar] [CrossRef] [PubMed]
- McGirt, M.J.; Chaichana, K.L.; Attenello, F.J.; Weingart, J.D.; Than, K.; Burger, P.C.; Olivi, A.; Brem, H.; Quinones-Hinojosa, A. Extent of Surgical Resection is Independently Associated With Survival in Patients With Hemispheric Infiltrating Low-Grade Gliomas. Neuropathology 2008, 63, 700–708. [Google Scholar] [CrossRef] [PubMed]
- Pichlmeier, U.; Bink, A.; Schackert, G.; Stummer, W. Resection and survival in glioblastoma multiforme: An RTOG recursive partitioning analysis of ALA study patients. Neuro-Oncology 2008, 10, 1025–1034. [Google Scholar] [CrossRef] [PubMed]
- Marbacher, S.; Klinger, E.; Schwyzer, L.; Fischer, I.; Nevzati, E.; Diepers, M.; Roelcke, U.; Fathi, A.-R.; Coluccia, D.; Fandino, J. Use of fluorescence to guide resection or biopsy of primary brain tumors and brain metastases. Neurosurg. Focus 2014, 36, E10. [Google Scholar] [CrossRef]
- Potapov, A.A.; Goryaynov, S.A.; Okhlopkov, V.A.; Shishkina, L.V.; Loschenov, V.B.; Savelieva, T.A.; Golbin, D.A.; Chumakova, A.P.; Goldberg, M.F.; Varyukhina, M.D.; et al. Laser biospectroscopy and 5-ALA fluorescence navigation as a helpful tool in the meningioma resection. Neurosurg. Rev. 2016, 39, 437–447. [Google Scholar] [CrossRef]
- Sanai, N.; Snyder, L.A.; Honea, N.J.; Coons, S.W.; Eschbacher, J.M.; Smith, K.A.; Spetzler, R.F. Intraoperative confocal microscopy in the visualization of 5-aminolevulinic acid fluorescence in low-grade gliomas. J. Neurosurg. 2011, 115, 740–748. [Google Scholar] [CrossRef]
- Zhang, C.; Boop, F.A.; Ruge, J. The use of 5-aminolevulinic acid in resection of pediatric brain tumors: A critical review. J. Neuro-Oncol. 2018, 141, 567–573. [Google Scholar] [CrossRef]
- Hervey-Jumper, S.L.; Berger, M.S. Maximizing safe resection of low- and high-grade glioma. J. Neuro-Oncol. 2016, 130, 269–282. [Google Scholar] [CrossRef]
- Motekallemi, A.; Jeltema, H.-R.; Metzemaekers, J.D.M.; Van Dam, G.M.; Crane, L.M.A.; Groen, R.J.M. The current status of 5-ALA fluorescence-guided resection of intracranial meningiomas—A critical review. Neurosurg. Rev. 2015, 38, 619–628. [Google Scholar] [CrossRef]
- Belykh, E.; Miller, E.J.; Hu, D.; Martirosyan, N.L.; Woolf, E.C.; Scheck, A.C.; Byvaltsev, V.A.; Nakaji, P.; Nelson, L.Y.; Seibel, E.J.; et al. Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma. World Neurosurg. 2018, 113, e51–e69. [Google Scholar] [CrossRef] [PubMed]
- Slof, J.; Valle, R.D.; Galvan, J. Análisis coste-efectividad de la cirugía del glioma maligno guiada por fluorescencia con ácido 5-aminolevulínicascencia con 5-aminolevulínico. Neurología 2014, 30, 163–168. [Google Scholar] [PubMed]
- Moore, G.E.; Peyton, W.T.; French, L.A.; Walker, W.W. The clinical use of fluorescein in neurosurgery; the localization of brain tumors. J. Neurosurg. 1948, 5, 392–398. [Google Scholar] [CrossRef]
- Waqas, M.; Shamim, M.S. Sodium fluorescein guided resection of malignant glioma. J. Pak. Med. Assoc. 2018, 68, 968–970. [Google Scholar]
- Murray, K.J. Improved surgical resection of human brain tumors: Part 1. A preliminary study. Surg. Neurol. 1982, 17, 316–319. [Google Scholar] [CrossRef]
- Yannuzzi, L.A.; Rohrer, K.T.; Tindel, L.J.; Sobel, R.S.; Costanza, M.A.; Shields, W.; Zang, E. Fluorescein Angiography Complication Survey. Ophthalmology 1986, 93, 611–617. [Google Scholar] [CrossRef]
- Kwan, A.S.; Barry, C.; McAllister, I.L.; Constable, I.J. Fluorescein angiography and adverse drug reactions revisited: The Lions Eye experience. Clin. Exp. Ophthalmol. 2006, 34, 33–38. [Google Scholar] [CrossRef]
- Kwiterovich, K.A.; Maguire, M.G.; Murphy, R.P.; Schachat, A.P.; Bressler, N.M.; Bressler, S.B.; Fine, S.L. Frequency of adverse systemic reactions after fluorescein angiography: Results of a prospective study. Ophthalmology 1991, 98, 1139–1142. [Google Scholar] [CrossRef]
- Novotny, H.R.; Alvis, D.L. A Method of Photographing Fluorescence in Circulating Blood in the Human Retina. Circulation 1961, 24, 82–86. [Google Scholar] [CrossRef]
- Stummer, W. Poor man’s fluorescence? Acta Neurochir. 2015, 157, 1379–1381. [Google Scholar] [CrossRef]
- Sun, W.; Kajimoto, Y.; Inoue, H.; Miyatake, S.-I.; Ishikawa, T.; Kuroiwa, T. Gefitinib enhances the efficacy of photodynamic therapy using 5-aminolevulinic acid in malignant brain tumor cells. Photodiagnosis Photodyn. Ther. 2013, 10, 42–50. [Google Scholar] [CrossRef] [PubMed]
- Schebesch, K.-M.; Hoehne, J.; Hohenberger, C.; Acerbi, F.; Broggi, M.; Proescholdt, M.A.; Wendl, C.; Riemenschneider, M.J.; Brawanski, A. Fluorescein sodium-guided surgery in cerebral lymphoma. Clin. Neurol. Neurosurg. 2015, 139, 125–128. [Google Scholar] [CrossRef]
- Schebesch, K.M.; Proescholdt, M.; Hohne, J.; Hohenberger, C.; Hansen, E.; Riemenschneider, M.J.; Ullrich, W.; Doenitz, C.; Schlaier, J.; Lange, M.; et al. Sodium fluorescein-guided resection under the YELLOW 560 nm surgical microscope filter in malignant brain tumor surgeryea feasibility study. Acta Neurochir (Wien.) 2013, 155, 693–699. [Google Scholar] [CrossRef] [PubMed]
- Höhne, J.; Hohenberger, C.; Proescholdt, M.; Riemenschneider, M.J.; Wendl, C.; Brawanski, A.; Schebesch, K.-M. Fluorescein sodium-guided resection of cerebral metastases—An update. Acta Neurochir. 2017, 159, 363–367. [Google Scholar] [CrossRef]
- Diaz, R.J.; Dios, R.R.; Hattab, E.M.; Burrell, K.; Rakopoulos, P.; Sabha, N.; Hawkins, C.; Zadeh, G.; Rutka, J.T.; Cohen-Gadol, A. Study of the biodistribution of fluorescein in glioma-infiltrated mouse brain and histopathological correlation of intraoperative findings in high-grade gliomas resected under fluorescein fluorescence guidance. J. Neurosurg. 2015, 122, 1360–1369. [Google Scholar] [CrossRef] [PubMed]
- Höhne, J.; Brawanski, A.; Schebesch, K.-M. Fluorescence-guided surgery of brain abscesses. Clin. Neurol. Neurosurg. 2017, 155, 36–39. [Google Scholar] [CrossRef]
- Acerbi, F.; Broggi, M.; Eoli, M.; Anghileri, E.; Cuppini, L.; Pollo, B.; Schiariti, M.; Visintini, S.; Orsi, C.; Franzini, A.; et al. Fluorescein-guided surgery for grade IV gliomas with a dedicated filter on the surgical microscope: Preliminary results in 12 cases. Acta Neurochir. 2013, 155, 1277–1286. [Google Scholar] [CrossRef]
- Schebesch, K.M. Levetiracetam versus phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy. J. Clin. Neurosci. 2012, 19, 99–100. [Google Scholar]
- Acerbi, F.; Cavallo, C.; Broggi, M.; Cordella, R.; Anghileri, E.; Eoli, M.; Schiariti, M.; Broggi, G.; Ferroli, P. Fluorescein-guided surgery for malignant gliomas: A review. Neurosurg. Rev. 2014, 37, 547–557. [Google Scholar] [CrossRef]
- Tanahashi, S.; Lida, H.; Dohi, S. An Anaphylactoid Reaction After Administration of Fluorescein Sodium During Neurosurgery. Anesthesia Analg. 2006, 103, 503. [Google Scholar] [CrossRef]
- Ozdamar, D.; Ihsan, A.; Tulay, H. Anaphylactic reaction after fluorescein sodium administration during intracranial surgery. J. Clin. Neurosci. 2011, 18, 430–431. [Google Scholar] [CrossRef]
- Nduom, E.K.; Yang, C.; Merrill, M.J.; Zhuang, Z.; Lonser, R.R. Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms. J. Neurosurg. 2013, 119, 427–433. [Google Scholar] [CrossRef] [PubMed]
- Stummer, W. Factors confounding fluorescein-guided malignant glioma resections: Edema bulk flow, dose, timing, and now: Imaging hardware? Acta Neurochir. 2015, 158, 327–328. [Google Scholar] [CrossRef]
- Wallace, M.B.; Meining, A.; Canto, M.I.; Fockens, P.; Miehlke, S.; Roesch, T.; Lightdale, C.J.; Pohl, H.; Carr-Locke, D.; Löhr, M.; et al. The safety of intravenous fluorescein for confocal laser endomicroscopy in the gastrointestinal tract. Aliment. Pharmacol. Ther. 2010, 31, 548–552. [Google Scholar] [CrossRef]
- Da Silva, C.E.; Braga-Silva, J.; Da Silva, V.D. Use of sodium fluorescein in skull base tumors. Surg. Neurol. Int. 2010, 1, 70. [Google Scholar] [CrossRef]
- Acerbi, F.; Broggi, M.; Broggi, G.; Ferroli, P. What is the best timing for fluorescein injection during surgical removal of high-grade gliomas? Acta Neurochir. 2015, 157, 1377–1378. [Google Scholar] [CrossRef] [PubMed]
- Stummer, W.; Götz, C.; Hassan, A.; Heimann, A.; Kempski, O. Kinetics of Photofrin II in Perifocal Brain Edema. Neuropathology 1993, 33, 1075–1082. [Google Scholar] [CrossRef]
- Russell, S.M.; Elliott, R.; Forshaw, D.; Golfinos, J.G.; Nelson, P.K.; Kelly, P.J. Glioma vascularity correlates with reduced patient survival and increased malignancy. Surg. Neurol. 2009, 72, 242–246. [Google Scholar] [CrossRef]
- Leon, S.P.; Folkerth, R.D.; Black, P.M. Microvessel density is a prognostic indicator for patients with astroglial brain tumors. Cancer 1996, 77, 362–372. [Google Scholar] [CrossRef]
- Rey-Dios, R.; Hattab, E.M.; Cohen-Gadol, A. Use of intraoperative fluorescein sodium fluorescence to improve the accuracy of tissue diagnosis during stereotactic needle biopsy of high-grade gliomas. Acta Neurochir. 2014, 156, 1071–1075. [Google Scholar] [CrossRef]
- Sanai, N.; Berger, M.S. Glioma Extent of Resection and Its Impact on Patient Outcome. Neuropathology 2008, 62, 753–766. [Google Scholar] [CrossRef] [PubMed]
- Hadjipanayis, C.G.; Widhalm, G.; Stummer, W. What is the surgical benefit of utilizing 5-aminolevulinic acid for fluorescence-guided surgery of malignant gliomas? Neurosurgery 2015, 77, 663–673. [Google Scholar] [CrossRef] [PubMed]
- Moiyadi, A.V.; Shetty, P. Objective assessment of utility of intraoperative ultrasound in resection of central nervous system tumors: A cost-eff ective tool for intraoperative navigation in neurosurgery. J. Neurosci. Rural. Pr. 2011, 2, 004–011. [Google Scholar] [CrossRef]
- Schebesch, K.M.; Proescholdt, M.; Brawanski, A. Fluorescein sodium in brain tumor surgerye response. Acta Neurochir. 2013, 155, 2253–2254. [Google Scholar] [CrossRef] [PubMed]
- Brawanski, A.; Acerbi, F.; Nakaji, P.; Cohen-Gadol, A.; Schebesch, K.M. Poor man-rich man fluorescence. Is this really the problem? Acta Neurochir. 2015, 157, 1959–1961. [Google Scholar] [CrossRef] [PubMed]
- Stummer, W. Fluorescein in brain metastasis and glioma surgery. Acta Neurochir. 2015, 157, 2199–2200. [Google Scholar] [CrossRef]
- Stockhammer, F. What does fluorescence depict in glioma surgery? Acta Neurochir. 2013, 155, 1479–1480. [Google Scholar] [CrossRef]
- Sankar, T.; Delaney, P.M.; Ryan, R.W.; Eschbacher, J.; Abdelwahab, M.; Nakaji, P.; Coons, S.W.; Scheck, A.C.; Smith, K.A.; Spetzler, R.F.; et al. Miniaturized Handheld Confocal Microscopy for Neurosurgery. Neuropathology 2010, 66, 410–418. [Google Scholar] [CrossRef]
- Martirosyan, N.L.; Eschbacher, J.M.; Kalani, M.Y.S.; Turner, J.D.; Belykh, E.; Spetzler, R.F.; Nakaji, P.; Preul, M.C. Prospective evaluation of the utility of intraoperative confocal laser endomicroscopy in patients with brain neoplasms using fluorescein sodium: Experience with 74 cases. Neurosurg. Focus 2016, 40, E11. [Google Scholar] [CrossRef]
- Schwake, M.; Stummer, W.; Molina, E.J.S.; Wölfer, J. Simultaneous fluorescein sodium and 5-ALA in fluorescence-guided glioma surgery. Acta Neurochir. 2015, 157, 877–879. [Google Scholar] [CrossRef]
- Yano, H.; Nakayama, N.; Ohe, N.; Miwa, K.; Shinoda, J.; Iwama, T. Pathological analysis of the surgical margins of resected glioblastomas excised using photodynamic visualization withboth5-aminolevulinicacid and fluorescein sodium. J. Neurooncol. 2017, 133, 389–397. [Google Scholar] [CrossRef] [PubMed]
- Molina, E.S.; Wölfer, J.; Ewelt, C.; Ehrhardt, A.; Brokinkel, B.; Stummer, W. Dual-labeling with 5–aminolevulinic acid and fluorescein for fluorescence-guided resection of high-grade gliomas: Technical note. J. Neurosurg. 2018, 128, 399–405. [Google Scholar] [CrossRef] [PubMed]
- Della Puppa, A.; Munari, M.; Gardiman, M.P.; Volpin, F. Combined Fluorescence Using 5-Aminolevulinic Acid and Fluorescein Sodium at Glioblastoma Border: Intraoperative Findings and Histopathologic Data About 3 Newly Diagnosed Consecutive Cases. World Neurosurg. 2019, 122, e856–e863. [Google Scholar] [CrossRef] [PubMed]
- Namikawa, T.; Sato, T.; Hanazaki, K. Recent advances in near-infrared fluorescence-guided imaging surgery using indocyanine green. Surg. Today 2015, 45, 1467–1474. [Google Scholar] [CrossRef]
- Alander, J.T.; Kaartinen, I.; Laakso, A.; Pätilä, T.; Spillmann, T.; Tuchin, V.V.; Venermo, M.; Välisuo, P. A Review of Indocyanine Green Fluorescent Imaging in Surgery. Int. J. Biomed. Imaging 2012, 2012, 1–26. [Google Scholar] [CrossRef]
- Sevick-Muraca, E.M.; Sharma, R.; Rasmussen, J.C.; Marshall, M.V.; Wendt, J.A.; Pham, H.Q.; Bonefas, E.; Houston, J.P.; Sampath, L.; Adams, K.E.; et al. Imaging of Lymph Flow in Breast Cancer Patients after Microdose Administration of a Near-Infrared Fluorophore: Feasibility Study. Radiology 2008, 246, 734–741. [Google Scholar] [CrossRef]
- Patel, J.; Marks, K.; Roberts, I.; Azzopardi, D.; Edwards, A.D. Measurement of Cerebral Blood Flow in Newborn Infants Using Near Infrared Spectroscopy with Indocyanine Green. Pediatr. Res. 1998, 43, 34–39. [Google Scholar] [CrossRef]
- Kuroiwa, T.; Kajimoto, Y.; Ohta, T. Development and Clinical Application of Near-Infrared Surgical Microscope: Preliminary Report. min-Minim. Invasive Neurosurg. 2001, 44, 240–242. [Google Scholar] [CrossRef]
- **g, Z.; Ou, S.; Ban, Y.; Tong, Z.; Wang, Y. Intraoperative assessment of anterior circulation aneurysms using the indocyanine green video angiography technique. J. Clin. Neurosci. 2010, 17, 26–28. [Google Scholar] [CrossRef]
- Raabe, A.; Beck, J.; Gerlach, R.; Zimmermann, M.; Seifert, V. Near-infrared Indocyanine Green Video Angiography: A New Method for Intraoperative Assessment of Vascular Flow. Neuropathology 2003, 52, 132–139. [Google Scholar] [CrossRef]
- De Oliveira, J.G.; Beck, J.; Seifert, V.; Teixeira, M.J.; Raabe, A. Assessment of Flow in Perforating Arteries During Intracranial Aneurysm Surgery Using Intraoperative Near-Infrared Indocyanine Green Videoangiography. Neuropathology 2008, 62, ONS-63. [Google Scholar] [CrossRef]
- Raabe, A.; Nakaji, P.; Beck, J.; Kim, L.J.; Hsu, F.P.K.; Kamerman, J.D.; Seifert, V.; Spetzler, R.F. Prospective evaluation of surgical microscope—Integrated intraoperative near-infrared indocyanine green videoangiography during aneurysm surgery. J. Neurosurg. 2005, 103, 982–989. [Google Scholar] [CrossRef]
- Ma, C.; Shi, J.-X.; Wang, H.; Hang, C.; Cheng, H.; Wu, W. Intraoperative indocyanine green angiography in intracranial aneurysm surgery: Microsurgical clip** and revascularization. Clin. Neurol. Neurosurg. 2009, 111, 840–846. [Google Scholar] [CrossRef] [PubMed]
- Li, J.; Lan, Z.; He, M.; You, C. Assessment of microscope-integrated indocyanine green angiography during intracranial aneurysm surgery: A retrospective study of 120 patients. Neurol. India 2009, 57, 453. [Google Scholar] [CrossRef] [PubMed]
- Dashti, R.; Laakso, A.; Niemelä, M.; Porras, M.; Hernesniemi, J. Microscope-integrated near-infrared indocyanine green videoangiography during surgery of intracranial aneurysms: The Helsinki experience. Surg. Neurol. 2009, 71, 543–550. [Google Scholar] [CrossRef] [PubMed]
- Paumgartner, G. The handling of indocyanine green by the liver. Schweiz. Med. Wochenschr. 1975, 105, 1–30. [Google Scholar] [PubMed]
- Wipper, S.H. Validierung der Fluoreszenzangiographie zur intraoperativen Beurteilung und Quantifizierung der Myokardperfusion [Validation of Fluorescence Angiography for Intraoperative Assessment and Quantification of Myocardial Perfusion]. Master’s Thesis, Faculty of Medicine, LMU München, Munich, Germany, 2006; pp. 18–23. OCLC 723710136(In German). [Google Scholar]
- Engel, E.; Schraml, R.; Maisch, T.; Kobuch, K.; König, B.; Szeimies, R.; Hillenkamp, J.; Bäumler, W.; Vasold, R. Light-Induced Decomposition of Indocyanine Green. Investig. Opthalmology Vis. Sci. 2008, 49, 1777–1783. [Google Scholar] [CrossRef] [PubMed]
- Sato, T.; Ito, M.; Ishida, M.; Karasawa, Y. Phototoxicity of Indocyanine Green under Continuous Fluorescent Lamp Illumination and Its Prevention by Blocking Red Light on Cultured Müller Cells. Investig. Opthalmology Vis. Sci. 2010, 51, 4337–4345. [Google Scholar] [CrossRef]
- Rhatigan, M.C.; Roxburgh, S.T.D. Indocyanine green angiography I: The normal angiogram, age related macular degeneration and inflammatory disease. Eye News 1996, 3, 25–31. [Google Scholar]
- Kochubey, V.I.; Kulyabina, T.V.; Tuchin, V.V.; Altshuler, G.B. Spectral Characteristics of Indocyanine Green upon Its Interaction with Biological Tissues. Opt. Spectrosc. 2005, 99, 560–566. [Google Scholar] [CrossRef]
No. | Study | n | His-Pat | Dose | Supply | GTR (%) | PFS-6 (%) | PFS (Months) | OS (Months) |
---|---|---|---|---|---|---|---|---|---|
1. | Stummer, et al. (2000) [16] | 52 | GBM | 20 mg/kg | 3 h before induction of anesthesia | 63.5 [33/52] | 20 | ||
2. | Stummer, et al. (2006) [27] | 139 | HGG | 20 mg/kg | 2–4 h before induction of anesthesia | ||||
Study group | 139 | WHO IV—135 WHO III—4 | 65 [90/139] | 41.0 | >55 y–14.1 <55y–18 | ||||
Control group | 131 | WHO IV—125 WHO III—5 | 36 [57/131] | 21.1 | >55 y–11.4 <55 y–17.5 | ||||
3. | Nabavi, et al. (2009) [46] | 36 | HGG (recurrent) WHO IV—21 WHO III—13 Progression of LGG—2 | 20 mg/kg | 3 h before induction of anesthesia | 19.4% [7/36] | 7.4 9.9 | ||
4. | Feigl, et al. (2010) [43] | 18 | HGG WHO IV—15 Primary—14 Recurrent—1 WHO III—3 | 20 mg/kg | 6 h before surgery | 88.9 | |||
5. | Diez Valle, et al. (2010) [32] | 36 | GBM | 20 mg/kg | 2–4 before induction of anesthesia | 83.3 [30/36] >98–100% | |||
28 | Primary | 82% [23/28] | 6.5 | 15.7 | |||||
8 | Recurrent | 87.5% [7/8] | 5.3 | 7.9 | |||||
6. | Tsugu, et al. (2011) [42] | 11 | HGG WHO IV—9 WHO III—2 | 1000 mg | 2–4 before induction of anesthesia | 54.5 [6/11] | |||
7. | Idoate, et al. (2011) [36] | 30 | GBM Recurrent—9 | 20 mg/kg | 2–4 h before surgery | 83.3 [25/30] >98–100% | |||
8. | Schucht, et al. (2012) [37] | 53 | GBM | 20 mg/kg | 2–4 h before induction of anesthesia | 96.2 [51/53] n.r.e. >0.175–96.2 cm3 [51/53] n.r.e.: 89% [47/53] >98–96%—51/53 >90–98%—52/53 | |||
9. | Tejada-Solis, et al. (2012) [35] | 65 | GBM | 20 mg/kg | 2 h before induction of anesthesia | 78.5 [51/65] | 16 | ||
10. | Eyupoglu, et al. (2012) [40] | 37 | HGG | 20 mg/kg | 3 h before induction of anesthesia | 56.8 [21/37] | |||
WHO IV—30 | 63.3 [19/30] | ||||||||
WHO III—7 | 28.6 [2/7] | ||||||||
11. | Cortnum, et al. (2012) [41] | 13 | HGG–WHO IV | 1500 mg | 2–4 h before surgery | 70 [7/10] 54 [7/13] | |||
12 | GBM | Total—7/12 Near total—4/12 | |||||||
1 | Other—PNET–WHO IV | Near total—1/1 | |||||||
12. | Roessler, et al. (2012) [39] | 10 | GBM | 20 mg/kg | no data | 50 [5/10] | |||
13. | Pastor, et al. (2013) [44] | 30 | HGG | 20 mg/kg | 2–4 h before induction of anesthesia | 66.7 [24/36] >98%—66.7 [24/36] >95%—5.6 [2/36] >90%—19.4 [7/36] | |||
14. | Diez Valle, et al. (2014) [31] | 251 | HGG | no data | no data | 69.1 | |||
Study group | 131 | 90.1 [118/131] | 71.2 | ||||||
WHO IV—122 | 69.1 | ||||||||
WHO III—9 | |||||||||
Control group | 120 | 66.7 [80/120] | 52.5 | ||||||
WHO IV—102 | 48.1 | ||||||||
WHO III—18 | |||||||||
15. | Della Pupa, et al. (2014) [33] | 94 | HGG | 20 mg/kg | 2–4 h before surgery | 92.6 >98%—93 [88/94] >90%—100 [94/94] | |||
Primary—61 Recurrent—33 | 93 [57/61] 79 [31/33]] | ||||||||
WHO IV—81 WHO III—13 | 96 [78/81] 79 [10/13] | ||||||||
16. | Piquer, et al. (2014) [38] | 30 | HGG WHO IV—23 WHO III—4 MET—3 | 20 mg/kg | 6 h before surgery | 74.1 [20/27] 78.2 [18/23] 50 [2/4] 100 [3/3] | |||
17. | Della Pupa, et al. (2017) [34] | 79 | GBM | 20 mg/kg | 2–4 h before surgery | 77.2 | 11 | 21 | |
18. | Ming Chan, et al. (2018) [45] | 16 | HGG WHO IV—10 WHO III—2 LGG—3 Other—1 | 20 mg/kg | 3–4 before induction of anesthesia | 68.8 [11/16] Total—56.3 [9/16] >95%—12.5 [2/16] >90%—31.25 [5/16] |
No. | Study | n | Hist-Pat | Equipment | Dose | Supply | GTR (%) | PFS-6 (%) | PFS (Months) | OS (Months) |
---|---|---|---|---|---|---|---|---|---|---|
1. | Kuroiwa, et al. (1998) [48] | 8 | HGG | microscope with filter | 8 mg/kg | after durotomy | 100 | 7.4 | ||
2. | Kuroiwa, et al. (1999) [49] | 30 | HGG | microscope with filter | 8 mg/kg | before durotomy | 83.3 | |||
3. | Kuroiwa, et al. (1999) [50] | 14 | HGG | microscope with filter | 8 mg/kg | before durotomy | 71.4 | |||
4. | Shinoda, et al. (2003) [55] | 105 | GBM | without microscope | 20 mg/kg | after durotomy | ||||
Study group | 32 | 84.4 | 15 | |||||||
Control group | 73 | 30.1 | 13 | |||||||
5. | Koc, et al. (2008) [56] | 80 | GBM | standardmicroscope | 20 mg/kg | before durotomy | ||||
Study group | 47 | 83 | 11 | |||||||
Control group | 33 | 55 | 10.5 | |||||||
6. | Okuda, et al. (2012) [57] | 7 | GBM | microscope with filter | 20 mg/kg | after durotomy | 71.4 | |||
7. | Chen, et al. (2012) [54] | 22 | glioma | without microscope | 15–20 mg/kg | before durotomy | 80 | |||
Study group | 10 | WHO II—4WHO III—3WHO IV—3 | 7.2 | |||||||
Control group | 12 | WHO II—5WHO III—3WHO IV—4 | 5.4 | |||||||
8. | Acerbi (2013) [52] | 20 | HGG | microscope with filter | 5–10 mg/kg | before skin incision | 80 | 71.4 | 11 | |
1 | other | 100 | ||||||||
19 | GBM | 78.9 | ||||||||
9. | Hamamcioglu, et al. (2016) [47] | 19 | HGG | microscope with filter | 2–4 mg/kg | after induction of anesthesia | 68.42 | |||
6 | WHO III | |||||||||
13 | GBM | |||||||||
10. | Catapano, et al. (2017) [53] | 48 | HGG | microscope with filter | 5 mg/kg | after induction of anesthesia | ||||
Study group | 23 | WHO III—1WHO IV—22 | 82.6 | |||||||
Control group | 25 | WHO III—1WHO IV—24 | 52 | |||||||
11. | Neira, et al. (2017) [58] | 32 | GBM | microscope with filter | 3 mg/kg | after induction of anesthesia | 84 | |||
20 | primary | |||||||||
12 | recurrent | |||||||||
12. | Acerbi, et al. (2018) [51] | 46 | HGG | microscope with filter | 5–10 mg/kg | after induction of anesthesia | 82.6 | 56.6 | 12 | |
2 | other | 100 | ||||||||
44 | GBM | 81.8 | ||||||||
13. | Hohne, et al. (2019) [59] | 106 | GBM(recurrent) | microscope with filter | 5 mg/kg | beforecraniotomy | 84 |
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Mazurek, M.; Kulesza, B.; Stoma, F.; Osuchowski, J.; Mańdziuk, S.; Rola, R. Characteristics of Fluorescent Intraoperative Dyes Helpful in Gross Total Resection of High-Grade Gliomas—A Systematic Review. Diagnostics 2020, 10, 1100. https://doi.org/10.3390/diagnostics10121100
Mazurek M, Kulesza B, Stoma F, Osuchowski J, Mańdziuk S, Rola R. Characteristics of Fluorescent Intraoperative Dyes Helpful in Gross Total Resection of High-Grade Gliomas—A Systematic Review. Diagnostics. 2020; 10(12):1100. https://doi.org/10.3390/diagnostics10121100
Chicago/Turabian StyleMazurek, Marek, Bartłomiej Kulesza, Filip Stoma, Jacek Osuchowski, Sławomir Mańdziuk, and Radosław Rola. 2020. "Characteristics of Fluorescent Intraoperative Dyes Helpful in Gross Total Resection of High-Grade Gliomas—A Systematic Review" Diagnostics 10, no. 12: 1100. https://doi.org/10.3390/diagnostics10121100