Contrast Enhanced EUS for Predicting Solid Pancreatic Neuroendocrine Tumor Grade and Aggressiveness
, Valeria Poletti 1,2, Alessandro Zerbi 2,7, Andrea Gerardo Lania 8, Alexia Francesca Bertuzzi 9, Paola Spaggiari 10, Vittorio Pedicini 11, Marcello Rodari 12, Pietro Fusaroli 13, Andrea Lisotti 13, Andrew Ofosu 14, Alessandro Repici 2,3 and Benedetto Mangiavillano 1,2,*Round 1
Reviewer 1 Report
Dear Dr. Gianluca & the Group,
I was asked to provide a review comments on the included manuscript. Can you provide some examples with color images of the lesions which would enhance the quality of the manuscript.
Best wishes
Author Response
We have appreciated your advice; we added some signature images that could enhance the quality of the abstract.
Reviewer 2 Report
Thank you for your excellent work. CE-EUS may be a reasonable modality of determining the diagnosis and aggressiveness of P-NET, although histological assessment is definitely required. I would like you to put some informative points to make more CE-EUS familiar to the readers.
1. Please use some EUS pictures or show some schema when EUS detects PNET aggressive if available.
2. I understand some contrast media for CE-EUS are available in the market. Please clarify what contrast media the authors in Table 1 used for their research.
Thank you
Author Response
We have deeply appreciated your advices;
1 We added some images explicative of the contrast-enhanced EUS,
2 We have inserted a new column with the specification of the contrast used in the paper.
