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The Role of OCT in Follow-Up of Fungal Keratitis Caused by Beauveria bassiana in Contact Lens Wearer

by
Cristina Martínez-Gil
1,*,
María José Roig-Revert
1,
Ester Fernández-López
1,
Rosa María González-Pellicer
2,3,
Juan José Camarena-Miñana
2,3 and
Cristina Peris-Martínez
1,4
1
Fundación de Oftalmología Médica de la Comunitat Valenciana, 46015 Valencia, Spain
2
Department of Microbiology, Hospital Univeristari Doctor Peset, 46017 Valencia, Spain
3
Department of Microbiology and Ecology, Universitat de Valencia (UV), 46010 Valencia, Spain
4
Department of Surgery-Ophthalmology, Universitat de Valencia (UV), 46010 Valencia, Spain
*
Author to whom correspondence should be addressed.
Diagnostics 2024, 14(13), 1382; https://doi.org/10.3390/diagnostics14131382
Submission received: 22 May 2024 / Revised: 17 June 2024 / Accepted: 26 June 2024 / Published: 28 June 2024
(This article belongs to the Special Issue Optical Coherence Tomography in Diagnosis of Ophthalmology Disease)

Abstract

 A 25-year-old Caucasic female was referred to our clinic after suffering from infectious keratitis in the right eye for a month. The patient was a contact lens user and had no history of ocular trauma. Furthermore, the patient did not report any relevant antecedent. The main complaint was intense photophobia and pain. Infectious keratitis remains one of the main complications of contact lens wear and can become a therapeutic challenge in some patients. Although the most frequent causal agent is bacterial, other causes such as herpes virus, Acanthamoeba or fungi should be considered when antimicrobial therapy does not work as expected clinically. Fungal keratitis normally appears on previously damaged corneas, but it can also develop in contact lens wearers. Beauveria bassiana is an unusual pathogen which has been diagnosed more frequently lately per the clinical reports in the last 30 years, so it can be included in the diagnostic scheme when a fungal keratitis is suspected. In clinical management, AS-OCT may be a functional tool to assess the evolution and monitor the response to microbial agents and surgery. Although more studies are needed, some characteristic features have been described and can help to diagnose a fungal keratitis against other infections. AS-OCT can also play an important role in monitoring the corneal scarring after the keratitis episode, and it may be useful to plan post-infection therapy for visual rehabilitation.
Keywords: keratitis; fungal; optical coherence tomography keratitis; fungal; optical coherence tomography

Share and Cite

MDPI and ACS Style

Martínez-Gil, C.; Roig-Revert, M.J.; Fernández-López, E.; González-Pellicer, R.M.; Camarena-Miñana, J.J.; Peris-Martínez, C. The Role of OCT in Follow-Up of Fungal Keratitis Caused by Beauveria bassiana in Contact Lens Wearer. Diagnostics 2024, 14, 1382. https://doi.org/10.3390/diagnostics14131382

AMA Style

Martínez-Gil C, Roig-Revert MJ, Fernández-López E, González-Pellicer RM, Camarena-Miñana JJ, Peris-Martínez C. The Role of OCT in Follow-Up of Fungal Keratitis Caused by Beauveria bassiana in Contact Lens Wearer. Diagnostics. 2024; 14(13):1382. https://doi.org/10.3390/diagnostics14131382

Chicago/Turabian Style

Martínez-Gil, Cristina, María José Roig-Revert, Ester Fernández-López, Rosa María González-Pellicer, Juan José Camarena-Miñana, and Cristina Peris-Martínez. 2024. "The Role of OCT in Follow-Up of Fungal Keratitis Caused by Beauveria bassiana in Contact Lens Wearer" Diagnostics 14, no. 13: 1382. https://doi.org/10.3390/diagnostics14131382

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