The Placenta as a Target of Epigenetic Alterations in Women with Gestational Diabetes Mellitus and Potential Implications for the Offspring
Abstract
:1. Introduction
2. Insulin Sensitivity in Pregnancy
The Role of the Placenta
3. Gestational Diabetes Mellitus and Adverse Effects on the Offspring
4. Alterations in the Placenta in Women with GDM
4.1. Epigenetic Modifications in the Placenta Caused by GDM
4.2. Placental DNA Methylation
4.3. miRNA Expression in the Placenta
4.4. Epigenetic Alterations in the Offspring and Potential Implications
5. Concluding Remarks
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Lizárraga, D.; García-Gasca, A. The Placenta as a Target of Epigenetic Alterations in Women with Gestational Diabetes Mellitus and Potential Implications for the Offspring. Epigenomes 2021, 5, 13. https://doi.org/10.3390/epigenomes5020013
Lizárraga D, García-Gasca A. The Placenta as a Target of Epigenetic Alterations in Women with Gestational Diabetes Mellitus and Potential Implications for the Offspring. Epigenomes. 2021; 5(2):13. https://doi.org/10.3390/epigenomes5020013
Chicago/Turabian StyleLizárraga, Dennise, and Alejandra García-Gasca. 2021. "The Placenta as a Target of Epigenetic Alterations in Women with Gestational Diabetes Mellitus and Potential Implications for the Offspring" Epigenomes 5, no. 2: 13. https://doi.org/10.3390/epigenomes5020013