Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 79

Special Issue Editor


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Guest Editor
Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania
Interests: non-coding RNAs; transcriptomics; chromatin conformation; extracellular vesicles; exosomes; human adipose-derived stem cells; stem cell differentiation; neurogenesis; adipogenesis; osteogenesis; tissue engineering; biocompatibility; biomaterials; magnetic nanoparticles
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Special Issue Information

Dear Colleagues,

We are pleased to invite you to explore the dynamic landscape of EVs research, starting from novel experimental approaches for isolation and characterization, investigation of their cargo and impact on the immediately neighbouring millieu, to the potential use of these EVs as biomarkers in differentiation processes, as well as in disease diagnosis and prognosis. Extracellular vesicles (EVs) are membrane-derived nanovesicles secreted by living cells which function as potent mediators of intercellular communication. Cargos in EVs can serve as external stimuli for recipient cells, hence influencing the intercellular communication pathway under certain physiological and pathological conditions. Nevertheless, EVs have gained particular interest as nanosized vehicles for delivery of molecular components, thus aiming to become an important therapeutic tool to fight against disease.

In this context, the aim of this special issue is to highlight the biological role of EVs during stem cell differentiation stages, during development and during pathophysiological processes, including their potential use as biomarkers for monitoring and improving disease diagnosis and progression.

Both original articles and reviews are welcome for submission. Potential research areas include (but are not limited to) research on new technologies developed for EVs isolation, detection and separation; their possible use as potential therapeutic targets; their importance as bio-vehicles for the transfer and delivery of therapeutic cargos. This Special Issue will give readers insights about the latest discoveries and advances regarding EVs function in disease progression and/or prevention.

We look forward to receiving your contributions.

Dr. Sorina Dinescu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at mdpi.longhoe.net by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • stem cell biology
  • stem cell differentiation
  • adipogenesis
  • neurogenesis
  • extracellular vesicles in stem cell differentiation
  • ncRNAs
  • tumor microenvironment
  • intercellular communication

Published Papers

This special issue is now open for submission.
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