Hypersensitivity Pneumonitis: A Complex Lung Disease
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".
Deadline for manuscript submissions: 25 October 2024 | Viewed by 65
Special Issue Editor
Interests: antimicrobial resistance; microbiology; parasitology; micology; lung disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleague,
Hypersensitivity pneumonitis (HP) is a complex immune-mediated lung disease, that involves lung parenchyma and respiratory tract of susceptible and sensitised subjects in response to a repeated and prolonged inhalation of several different antigens or mixture of antigens. The exposure leads to non-IgE-mediated allergic reaction characterized by lymphocytic inflammation, frequently granulomatous, located in peripheral airways. Actually, there are more than 200 antigens in the workplace, at home and in recreational activities known to be a possible cause of HP, and they can be divided into two broad groups: (I) organic antigens, such as from bacteria, fungi, animal or plant proteins; (II) inorganic antigens, such as low molecular weight chemicals or metals. In HP, following antigen exposure, inflammation is mediated by humoral and cellular mechanisms, particularly by T-helper cells and antigen-specific immunoglobulin (IgG) antibodies, determining an accumulation of lymphocytes and the formation of granulomas. This Special Issue on "Hypersensitivity Pneumonitis: A Complex Lung Disease" welcomes original research and reviews with a focus on the most interesting and innovative development in the field of Hypersensitivity pneumonitis.
Potential topics will include:
- Molecular mechanisms involved
- Immunopathogenesis of the disease
- Laboratory tests and methods
- Inciting antigens
- Diagnosis
Dr. Jari Intra
Guest Editor
Manuscript Submission Information
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Keywords
- hypersensitivity pneumonitis
- immunoglobulin
- immunopathogenesis
- diagnosis
- lung disease
