Imaging Biomarkers for Pachychoroid Spectrum Disease

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 46

Special Issue Editors


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Guest Editor
Department of Ophthalmology, First Hospital of China Medical University, Shenyang 110001, China
Interests: the interpretation of fundus multi-modal imaging; choroidal disease; anti-VEGF and laser therapy; genetic diagnosis of retinal disease and AI in ophthalmology
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Guest Editor
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China
Interests: age-related macular degeneration; polypoidal choroidal vasculopathy; punctate inner choroidopathy; fundus multi-modal imaging
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, China
Interests: vtreoretinal disease; macular disease; fundus fluorescein angiography; retinal laser photocoagulation therapy; retinal disease research
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Pachychoroid spectrum disease (PSD) encompasses a set of macular disorders secondary to an abnormally thick choroid, including pachychoroid pigment epitheliopathy, focal choroidal excavation, peripapillary pachychoroid syndrome, central serous chorioretinopathy, pachychoroid neovasculopathy, and polypoidal choroidal vasculopathy, to name a few.

Like age-related macular degeneration, PSD is an entity of progressive bilateral choroidal vasculature malfunction with a continuous course from the early stage of uncomplicated pachychoroid and pachydrusen to the late stage of neovascular and atrophic PSD.

The underlying etiology and mechanism of PSD are probably due to the metabolic disorders of both catecholamine and thyroid-related hormones, as well as vortex vein congestion.

Multi-model imaging has been employed to investigate the mechanism, severity, and prognosis of PSD, which includes optical coherence tomography (OCT), OCT angiography (OCTA), and indocyanine green angiography. Meanwhile, several imaging biomarkers are introduced to achieve the purpose set out above, for example, subfoveal choroidal thickness and choroidal vascular index. At the same time, artificial intelligence (AI) deep learning is gradually being integrated into the selection of effective evaluating parameters.

The purpose of this Special Issue is to investigate the latest effective imaging biomarkers for PSD, expecting to better reveal its underlying mechanism, assess its severity, and predict its prognosis. Moreover, we would also like to include the novel research on AI deep learning in this field.

Prof. Dr. Rui Hua
Prof. Dr. Feng Wen
Prof. Dr. Meixia Zhang
Guest Editors

Manuscript Submission Information

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Keywords

  • pachychoroid spectrum disease
  • peripapillary pachychoroid syndrome
  • central serous chorioretinopathy
  • pachychoroid neovasculopathy
  • polypoidal choroidal vasculopathy
  • pachychoroid pigment epitheliopathy
  • focal choroidal excavation
  • macular neovascularization
  • optical coherence tomography angiography
  • indocyanine green angiography

Published Papers

This special issue is now open for submission.
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