Special Issues

Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Research Trends and Applications of Hematopoietic Stem Cell Transplantation
edited by David C. Shyr and Robertson Parkman
submission deadline 28 Feb 2025 | Viewed by 24 | Submission Open
Keywords: hematopoietic stem cell transplant; conditioning regimen; immunology; graft-versus-host disease; gene therapy; transplant-related toxicities; alternative donor stem cell transplant; supportive care
(This special issue belongs to the Section Hematology)
Blood Disorders: Diagnosis, Management, and Future Opportunities submission deadline 28 Feb 2025 | Viewed by 23 | Submission Open
Keywords: blood disorders; biomarkers; personalized medicine; diagnosis; NGS; metabolomics; digital droplet PCR (ddPCR)
(This special issue belongs to the Section Hematology)
Advancements in Cardiac Electrophysiology through Biomedical Engineering for Abnormality Monitoring and Detection in Clinical Practice
edited by Ilaria Marcantoni and Michela Casella
submission deadline 28 Feb 2025 | Viewed by 23 | Submission Open
Keywords: electrocardiogram; cardiac electrophysiology; cardiac risk index; cardiac arrhythmias; electrocardiographic alternans; long QT syndrome; heart electrical system anomalies; monitoring of heart electrical system; prevention; biomedical engineering in electrocardiology; cardiac signal processing; cardiac image processing
(This special issue belongs to the Section Cardiology)
Orthopedic Surgery: Recent Advances and Prospects
edited by Mitchell K. Ng
submission deadline 28 Feb 2025 | Viewed by 23 | Submission Open
Keywords: orthopedic surgery; clinical updates; joint reconstruction; spine surgery; trauma; elective surgery; peri-operative management
(This special issue belongs to the Section Orthopedics)
Cutting Edge of Minimally Invasive Spine Surgery
edited by
submission deadline 28 Feb 2025 | Viewed by 22 | Submission Open
Keywords: spine surgery; minimally invasive surgery; spinal deformity; spine fusion; enabling technology; spinal navigation; robotic surgery; spine materials; spinal endoscopy
(This special issue belongs to the Section Orthopedics)
New Advances in Keratoplasty
edited by Cristina Bovone
submission deadline 28 Feb 2025 | Viewed by 21 | Submission Open
Keywords: lamellar keratoplasty; descemet strip** endothelial keratoplasty (DSAEK); descemet membrane endothelial keratoplasty (DMEK); deep anterior lamellar keratoplasty (DALK); keratoconus; corneal dystrophies; bullous keratopathy; anterior segment OCT
(This special issue belongs to the Section Ophthalmology)
Severe Infection and Antimicrobial Management in ICU
edited by Ming Chen
submission deadline 28 Feb 2025 | Viewed by 19 | Submission Open
Keywords: early diagnosis of bacteremia in ICUs; rational antibiotic treatment of bacteremia in ICUs; relationship between early diagnosis and antimicrobial management in ICUs
(This special issue belongs to the Section Infectious Diseases)
Autoimmunity—Affecting Different Organ Systems (from Guts to Brain)
edited by and Sebastian Saur
submission deadline 28 Feb 2025 | Viewed by 15 | Submission Open
Keywords: autoimmune diseases; inflammatory bowl diseases; rheumatological diseases; neuro-inflammatory diseases; immunosuppression; overlap syndromes; treatment options for autoimmune diseases
(This special issue belongs to the Section Immunology)
Advanced Strategy for Diagnosis and Treatment of Obstructive Sleep Apnea Syndrome (OSAS)
edited by
submission deadline 28 Feb 2025 | Viewed by 12 | Submission Open
Keywords: obstructive sleep apnea syndrome; diagnosis; obesity; treatment; CPAP; comorbidities; cardiovascular risk
(This special issue belongs to the Section Pulmonology)
High-Flow Nasal Cannula (HFNC) and Noninvasive Ventilation: What Is New in Acute, Chronic and Rehabilitation Settings? submission deadline 28 Feb 2025 | Viewed by 12 | Submission Open
Keywords: NIV; HFNC; noninvasive ventilation; acute respiratory insufficiency; chronic respiratory insufficiency
(This special issue belongs to the Section Pulmonology)
Current and Emerging Treatment Options in Skull Base Surgery and Neuro-Oncology
edited by Antonio Meola and Leonello Tacconi
submission deadline 28 Feb 2025 | Submission Open
Keywords: skull base; neuro-oncology; brain tumor; artificial intelligence; radiosurgery; targeted therapy; neuro endoscopy
(This special issue belongs to the Section Clinical Neurology)
New Diagnostic and Therapeutic Trends in Sepsis and Septic Shock
edited by Christian Zanza, , and
submission deadline 28 Feb 2025 | Submission Open
Keywords: sepsis; septic shock; diagnostics; therapeutics; biomarkers; critical care
(This special issue belongs to the Section Hematology)
Emerging Technologies for Dental Imaging
edited by
submission deadline 15 Mar 2025 | 2 articles | Viewed by 1316 | Submission Open
Keywords: dental imaging; dental MRI; caries; periodontitis; orthodontics; oral surgery; craniomaxillofacial surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Cardiomyopathies: Current Treatment and Future Options: Second Edition
edited by
submission deadline 15 Mar 2025 | Viewed by 38 | Submission Open
Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; restrictive cardiomyopathy; amyloid cardiomyopathy; arrhythmogenic right ventricular cardiomyopathy; non-dilated left ventricular cardiomyopathy
(This special issue belongs to the Section Cardiology)
Corneal Diseases and Corneal Transplantation: Current Updates and Perspectives
edited by Itay Lavy, and Michael Mimouni
submission deadline 20 Mar 2025 | Viewed by 58 | Submission Open
Keywords: corneal diseases; corneal transplantation; imaging techniques; pharmacological in-terventions; surgical interventions; tissue engineering
(This special issue belongs to the Section Ophthalmology)
Vitreoretinal Diseases: Current Treatment and Future Advances
edited by and Ted Maddess
submission deadline 20 Mar 2025 | Viewed by 13 | Submission Open
Keywords: age-related macular degeneration; chorioretinopathy; diabetic retinopathy; diagnostics targeting early stage diseases; therapeutics targeting early stage diseases; macular hole; retinal diseases
(This special issue belongs to the Section Ophthalmology)
Perioperative Anesthesia: State of the Art and the Perspectives
edited by
submission deadline 20 Mar 2025 | Submission Open
Keywords: preoperative risk evaluation; prehabilitation; hemodynamic monitoring; post-surgical monitoring; patient deterioration; human factors; non-technical skills; cognitive aids; anesthetic drugs; regional anesthesia; healthcare worker wellness
(This special issue belongs to the Section Anesthesiology)
Infective Endocarditis: What Is New in the Clinical Research: 2nd Edition
edited by
submission deadline 25 Mar 2025 | Viewed by 61 | Submission Open
Keywords: infective endocarditis; vegetation; native valve; prosthetic valve; aortic valve; mitral valve; cardiac device; bloodstream infection; bacteremia
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in the Diagnosis and Treatment of Hypertrophic Cardiomyopathy submission deadline 25 Mar 2025 | Viewed by 25 | Submission Open
Keywords: hypertrophic cardiomyopathy; left ventricular hypertrophy; diagnosis; multimodality imaging; genetics; treatment; risk stratification; outcome; biomarkers
(This special issue belongs to the Section Cardiology)
Diabetic Nephropathy: Current Standards and Future Directions
edited by , and Charles W. Heilig
submission deadline 25 Mar 2025 | Viewed by 7 | Submission Open
Keywords: diabetic nephropathy: standard of care; diabetic nephropathy: future directions; SGLT2 in diabetic nephropathy; markers for diabetic nephropathy; diabetic nephropathy in the elderly; diabetic nephropathy in renal transplant patients; finerenone in diabetic nephropathy
(This special issue belongs to the Section Nephrology & Urology)
Minimally Invasive Gastrointestinal Surgery: Clinical Updates and Challenges submission deadline 25 Mar 2025 | Submission Open
Keywords: robotic surgery; single-incision laparoscopic surgery; natural orifice transluminal endoscopic surgery (NOTES); endoscopic submucosal dissection (ESD); peroral endoscopic myotomy (POEM); Heller myotomy; bariatric surgery; hiatal hernia; gastric cancer; gastrointestinal surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Perspectives in Liver Transplantation and Biliary Complications
edited by Marco Maria Pascale and Francesco Frongillo
submission deadline 28 Mar 2025 | Viewed by 30 | Submission Open
Keywords: liver transplant; cholangiopathy; ischemia/reperfusion injury; machine perfusion; extended-criteria donors
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Vascular and Endovascular Surgery: Current Progress and Future Challenges
edited by Michael Keese and Martin Sigl
submission deadline 28 Mar 2025 | Viewed by 25 | Submission Open
Keywords: vascular; endovascular; surgery; therapy; aneurysm; vascular; PAD; venous; interdisciplinary
(This special issue belongs to the Section Vascular Medicine)
Clinical Management of Cardiac Arrhythmias and Arrhythmogenic Disorders submission deadline 30 Mar 2025 | Viewed by 23 | Submission Open
Keywords: arrhythmias; electrophysiology; antiarrhythmic drugs; implantable devices; risk stratification; genetics
(This special issue belongs to the Section Cardiology)
Current Status of Endovascular Therapy for Acute Ischemic Stroke—2nd Edition submission deadline 30 Mar 2025 | Viewed by 20 | Submission Open
Keywords: endovascular therapy (EVT); cerebrovascular disease; thrombectomy; thrombolysis; ischemic stroke; interventional stroke therapy
(This special issue belongs to the Section Clinical Neurology)
Innovations in Minimally Invasive Surgery (MIS) in Urology
edited by , Roberto Bianchi and Giuseppe Fallara
submission deadline 30 Mar 2025 | Submission Open
Keywords: minimally invasive surgery; artificial intelligence; laparoscopy; robotics; virtual reality; miniaturization; automation
(This special issue belongs to the Section Nephrology & Urology)
Pediatric Obesity: Causes, Prevention and Treatment
edited by
submission deadline 31 Mar 2025 | Viewed by 572 | Submission Open
Keywords: 1000 first days of life; childhood obesity; lipids; healthy lifestyle; fetal programming
(This special issue belongs to the Section Endocrinology & Metabolism)
Urinary Tract Infection: Current Treatment and Future Options
edited by
submission deadline 31 Mar 2025 | Viewed by 55 | Submission Open
Keywords: urinary tract infections (UTIs); antibiotic resistance; probiotics and alternative therapies; diagnostic advancements; urinary infection management
(This special issue belongs to the Section Nephrology & Urology)
Interaction Between Systemic Diseases and Oral Diseases
edited by
submission deadline 31 Mar 2025 | Viewed by 48 | Submission Open
Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Presbyopia, Laser, Cataract and Refractive Surgery: State-of-the-Art Research
edited by
submission deadline 31 Mar 2025 | Viewed by 39 | Submission Open
Keywords: corneal grafts; cataract surgery; refractive surgery; presbyopia; laser; intraocular lenses
(This special issue belongs to the Section Ophthalmology)
Current Advances and Future Perspectives in Sports Cardiology
edited by
submission deadline 31 Mar 2025 | Viewed by 33 | Submission Open
Keywords: sports; exercise; arrhythmias; athlete’ s heart; cardiopulmonary exercise testing; heart failure
(This special issue belongs to the Section Cardiology)
Point of Care Sonography, an Essential Tool for Anesthesiology and Acute Care
edited by and Se-Chan Kim
submission deadline 31 Mar 2025 | Viewed by 27 | Submission Open
Keywords: ultrasound; anesthesia; acute care; critical care; regional anesthesia; vascular access; lung ultrasound; echocardiography; gastric ultrasound; point of care
(This special issue belongs to the Section Anesthesiology)
Clinical Advances in Cartilage Repair and Regeneration
edited by Akira Tsujii and Kazunori Shimomura
submission deadline 31 Mar 2025 | Viewed by 27 | Submission Open
Keywords: cartilage; regenerative therapy; stem cell therapy; scaffold; orthobiologics; osteoarthritis
(This special issue belongs to the Section Orthopedics)
Chronic Kidney Disease: Clinical Challenges and Management submission deadline 31 Mar 2025 | Viewed by 27 | Submission Open
Keywords: chronic kidney disease; clinical trial; end-stage renal disease; kidney dysfunction; management; challenge
(This special issue belongs to the Section Nephrology & Urology)
Hemodialysis: Clinical Updates and Advances
edited by
submission deadline 31 Mar 2025 | Viewed by 25 | Submission Open
Keywords: hemodiafiltration; medium cut-off membranes; expanded hemodialysis; vascular calcifications; renal anemia; vas-cular access; arterio-venous fistula; anticoagulation; outcomes
(This special issue belongs to the Section Nephrology & Urology)
Perspectives in Atrial Fibrillation: Managing Comorbidities, Recurrence, and Therapies
edited by Zsofia Drobni
submission deadline 31 Mar 2025 | Viewed by 18 | Submission Open
Keywords: atrial fibrillation; comorbidities; recurrence; therapies; catheter ablation; anticoagulants; antithrombotic
(This special issue belongs to the Section Cardiology)
State of the Art in Interventional Cardiology
edited by Antonios Karanasos
submission deadline 31 Mar 2025 | Viewed by 18 | Submission Open
Keywords: interventional cardiology; intravascular imaging; structural interventions; TAVI; vascular access; percutaneous coronary intervention; coronary stenting; cardiovascular diseases
(This special issue belongs to the Section Cardiology)
Cutting-Edge Advances in Assisted Reproductive Technologies (ART) and In Vitro Fertilization (IVF)
edited by Itai Gat
submission deadline 31 Mar 2025 | Viewed by 17 | Submission Open
Keywords: assisted reproductive technologies (ART); in vitro fertilization (IVF); artificial intelligence; genetics and epigenetics; fertility preservation; male factor
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Clinical Perspectives on Physical Activity and Health in Children and Adolescents
edited by , and Rocío Gómez
submission deadline 31 Mar 2025 | Viewed by 10 | Submission Open
Keywords: physical activity; sedentary behavior; health promotion; childhood obesity; well-being; fitness
(This special issue belongs to the Section Clinical Pediatrics)
Ovarian Cancer: Clinical Updates and Advances
edited by
submission deadline 31 Mar 2025 | Viewed by 6 | Submission Open
Keywords: ovarian cancer; prehabilitation; ultrasound; radiologic staging; cytoreductive surgery; targeted treatment; prevention; screening
(This special issue belongs to the Section Obstetrics & Gynecology)
Surgical Treatment for Lung Cancer
edited by Piotr Gabryel, Cezary Piwkowski and Marek Ochman
submission deadline 31 Mar 2025 | Viewed by 5 | Submission Open
Keywords: lung cancer; surgery; minimally invasive surgery; immunotherapy; enhanced recovery after surgery; segmentectomy
(This special issue belongs to the Section Pulmonology)
Orthodontics: Current Advances and Future Options submission deadline 31 Mar 2025 | Viewed by 4 | Submission Open
Keywords: digital orthodontics; functional devices; cranial growth; orthodontic therapy; customized devices
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Management and Outcomes in Wound Healing
edited by Carlotta Scarpa
submission deadline 31 Mar 2025 | Submission Open
Keywords: acute wounds; chronic wounds; burns; pressure ulcers; regenerative medicine
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Anesthesia and Sedation for Out-of-Operating-Room Procedures
edited by Basavana Gouda Bharamana Goudra
submission deadline 31 Mar 2025 | Submission Open
Keywords: gastrointestinal endoscopy; bronchoscopy; electrophysiological procedures; electroconvulsive therapy; out-of-operating-room anesthesia
(This special issue belongs to the Section Anesthesiology)
Clinical Role of Neuroinflammation in Disease
edited by
submission deadline 10 Apr 2025 | Submission Open
Keywords: neuroinflammation; brain tissues; Parkinson's Disease; Alzheimer's Disease; multiple sclerosis; amyotrophic lateral sclerosis; encephalitis; traumatic brain injury; epilepsy; encephalopathy; systemic inflammation; colonic inflammation; gut-brain axis; autoimmune disorders; therapeutics
(This special issue belongs to the Section Immunology)
Trends and Innovations in Regenerative Medicine and Non-surgical Aesthetics
edited by , William R. Webb, Jean D.A. Carruthers and Afshin Mosahebi
submission deadline 20 Apr 2025 | Viewed by 85 | Submission Open
Keywords: regenerative medicine; non-surgical aesthetics; stem cell therapy; ATMPs; skin rejuvenation; anti-aging treatments; growth factors; bioactive molecules; botulinum toxin A; dermal fillers; energy devices; AI in aesthetics; patient satisfaction; safety and efficacy; regulatory considerations
(This special issue belongs to the Section Epidemiology & Public Health)
Treatment Personalization in Clinical Psychology and Psychotherapy
edited by
submission deadline 20 Apr 2025 | Viewed by 12 | Submission Open
Keywords: treatment personalization; clinical psychology; psychotherapy; personalized treatment; psychosomatic interventions; co** and personalization
(This special issue belongs to the Section Mental Health)
One Size Does Not Fit All: New Strategies to Improve Overall Health and Physical Activity Behavior in Vulnerable Populations submission deadline 30 Apr 2025 | 5 articles | Viewed by 4807 | Submission Open
Keywords: chronic diseases; vascular function; aging; sedentarism; active breaks; exercise; respiratory muscle training; hostile environments
(This special issue belongs to the Section Sports Medicine)
Advancements in Venous Thrombosis Management: From Prevention to Long-Term Care
edited by
submission deadline 30 Apr 2025 | Viewed by 48 | Submission Open
Keywords: venous thromboembolism; post-thrombotic syndrome; direct oral anticoagulant; pulmonary embolism; thrombosis; factor xia inhibitors; thrombolysis; cancer; antiphospholipid syndrome; catheter-directed thrombolysis; inferior vena cava filters
(This special issue belongs to the Section Vascular Medicine)
Challenges and Opportunities in Geriatric Nephrology and Urology
edited by Giulio Romano
submission deadline 20 May 2025 | Viewed by 67 | Submission Open
Keywords: kidney disease; elderly patient; epidemiology; pharmacological therapy; lifestyle diet
(This special issue belongs to the Section Nephrology & Urology)
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