G-quadruplexes in Chemical Biology and Drug Discovery
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 49
Special Issue Editors
Interests: solid-phase synthesis; chemistry of nucleosides, nucleotides, and oligonucleotides; L-sugars; platinum complexes; heterocycles; bioorganic chemistry
Special Issues, Collections and Topics in MDPI journals
Interests: solid-phase synthesis; chemistry of nucleosides, nucleotides, and oligonucleotides; heterocycles; bioorganic chemis-try; G-quadruplex; supramolecular chemistry
Special Issue Information
Dear Colleagues,
G-quadruplexes are non-canonical four-stranded DNA superstructures formed by guanine-rich sequences. These structures have garnered significant attention in recent years due to their involvement in various biological processes, such as genomic regulation and stability, cancer progression, and neurodegenerative diseases. In addition to being powerful biological tools, G-quadruplexes have also been proven to be valuable building blocks for the construction of new probes and biomaterials. Accordingly, understanding and controlling the G-quadruplex structuration process offers a significant contribution to the advancement of biomedical research and the development of innovative therapeutic strategies. The aim of this Special Issue is to collect articles and reviews focused on the most recent findings in the G-quadruplex field and the potential applications of G-quadruplexes in chemical biology and drug discovery.
Dr. Stefano D’Errico
Prof. Dr. Gennaro Piccialli
Guest Editors
Dr. Maria Marzano
Guest Editor Assistant
Manuscript Submission Information
Manuscripts should be submitted online at mdpi.longhoe.net by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- DNA
- G-quadruplex
- telomeres
- supramolecular chemistry
- oligonucleotides
- drug discovery
- chemical biology
