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Molecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Gaseous Neurotransmitter Nitric Oxide: A Potential Therapeutic Target for Neuropsychiatric and Neurodegenerative Disorders

edited by

Nikolaos Pitsikas

submission deadline 30 Jun 2024 | 4 articles | Viewed by 5140

Keywords: nitric oxide; biological targets; pharmacology; neuropsychiatric disorders; neurodegenerative disorders

(This special issue belongs to the Section Applied Chemistry)

Miniaturized Sensors in Analytical Spectroscopy/Spectrometry

edited by

Justyna Grabska

Christian Huck

and

Krzysztof Bernard Bec

submission deadline 30 Jun 2024 | 3 articles | Viewed by 5050

Keywords: spectroscopy; spectrometry; analytical chemistry; chemometrics; data analysis; hand-held; portable; miniaturized

(This special issue belongs to the Section Analytical Chemistry)

Discovery of Small Molecules for Cancer Therapy: Current Challenges, Recent Trends, and Future Perspectives

edited by

Mehlika Dilek Altıntop

and

Ahmet Özdemir

submission deadline 30 Jun 2024 | 3 articles | Viewed by 4934

Keywords: cancer; targeted therapy; anticancer drug discovery; lead identification; small molecules; cancer-related targets; signaling pathways related to cancer; emerging approaches to anticancer drug design

(This special issue belongs to the Section Medicinal Chemistry)

Natural Compounds for Disease and Health II

edited by

George P.H. Leung

and

**g**g Li

submission deadline 30 Jun 2024 | 3 articles | Viewed by 4663

Keywords: natural products; phytochemistry; structure– activity relationship; mechanism of action; anti-aging; cancer; cardiovascular diseases; digestive diseases; endocrine disorders; immune diseases; infections; inflammation; liver diseases; metabolic diseases; musculoskeletal diseases; neurodegenerative diseases; pain; psychiatric diseases; renal diseases; respiratory diseases

(This special issue belongs to the Section Natural Products Chemistry)

Electrokinetic Motions of Colloidal Particles and Polymeric Fluid Mechanics

edited by

Eric Lee

submission deadline 30 Jun 2024 | 4 articles | Viewed by 4575

Keywords: electrophoresis; diffusiophoresis; dielectrophoresis; micro- and nanofluidics; liquid droplets; polymeric fluid mechanics; ionic liquids

(This special issue belongs to the Section Physical Chemistry)

Isolation, Synthesis and Biological Activity of Polysaccharides

edited by

Peng Lei

and

Sha Li

submission deadline 30 Jun 2024 | 3 articles | Viewed by 4566

Keywords: polysaccharide; isolation of polysaccharides; synthetic mechanism of polysaccharides; bioactivity of polysaccharides; structure– activity relationships of polysaccharides; modification of polysaccharides

(This special issue belongs to the Section Bioorganic Chemistry)

Surfactants and Interfaces

edited by

Bronisław Jańczuk

submission deadline 30 Jun 2024 | 3 articles | Viewed by 4516

Keywords: adsorption; aggregation; wettability; solubilization; foaming; emulsification

(This special issue belongs to the Section Macromolecular Chemistry)

Analytical Techniques in Pharmaceutical and Biomedical Analysis II

edited by

Franciszek Główka

and

Marta Karaźniewicz-Łada

submission deadline 30 Jun 2024 | 4 articles | Viewed by 4069

Keywords: bioanalysis; biopharmaceutics; HPLC; GC; electrophoresis; mass spectrometry; pharmacokinetics; pharmaceutical analysis; pharmaceutical formulation; plant materials; spectroscopy; validation

(This special issue belongs to the Section Analytical Chemistry)

Cell-Penetrating Peptides: A Promising Tool for Drug Delivery

edited by

Keykavous Parang

and

Sandeep Lohan

submission deadline 30 Jun 2024 | 3 articles | Viewed by 4064

Keywords: cell-penetrating peptide; targeted drug delivery; protein delivery; small molecule delivery; mode of cell penetration

(This special issue belongs to the Section Medicinal Chemistry)

New Advances in Radiopharmaceutical Sciences

edited by

Elisabeth Eppard

submission deadline 30 Jun 2024 | 4 articles | Viewed by 3893

Keywords: radiopharmacy/radiopharmaceuticals; radiochemistry; radionuclide therapy; theranostics; PET; SPECT; radiolabeling techniques; radionuclide production; nuclear medicine

(This special issue belongs to the Section Medicinal Chemistry)

Nanoparticles in Cellular Drug Delivery

edited by

Jessica M. Rosenholm

and

Jixi Zhang

submission deadline 30 Jun 2024 | 2 articles | Viewed by 3890

Keywords: nanomedicine; intracellular delivery; controlled release; cellular targeting; delivery of biologicals; gene transfection; precision therapy

(This special issue belongs to the Section Medicinal Chemistry)

Organophosphorus Chemistry: A New Perspective, 2nd Edition

edited by

Jakub Adamek

submission deadline 30 Jun 2024 | 4 articles | Viewed by 3804

Keywords: organophosphorus chemistry; P-compounds; reactivity of P-compounds; new methods for the synthesis of P-compounds; P-C bond formation; phosphorus-based organocatalysis; phosphonium-based ionic liquids (PILs); mitochondria-targeted triphenylphosphonium-based compounds; neutralization of P-compounds; chemical warfare agents; structure elucidation of P-compounds

(This special issue belongs to the Section Organic Chemistry)

Design and Synthesis of Novel Adsorbents for Pollutant Removal

edited by

Inna V. Melnyk

submission deadline 30 Jun 2024 | 4 articles | Viewed by 3746

Keywords: wastewater treatment; adsorbents; sustainable materials; adsorption mechanisms; surface chemistry; selective adsorption

(This special issue belongs to the Section Physical Chemistry)

Design, Construction, and Applications of New Mineral Functional Materials

edited by

Wenbo Wang

submission deadline 30 Jun 2024 | 4 articles | Viewed by 3483

Keywords: clay minerals and their composites (palygorskite; sepiolite; montmorillonite; rectorite; bentonite; vermiculite; laponite; kaolinite; and others); solid wastes with mineral properties and their composites (Iron tailings; coal gangue; semi-coke; and others); polymer/mineral composites; mineral-derived adsorbents; mineral-derived catalysts; purification of pollutants (organics; inorganic; and others); mineral-containing coatings; mineral-derived separation materials; mineral– carbon composites; mineral-based membranes; friction lubricating materials; energy-saving materials; mineral-derived antibacterial materials; mineral-based building materials; synthesis or evolution of minerals; the interaction between minerals and organic molecules; mineral-based pigments

(This special issue belongs to the Section Materials Chemistry)

Synthesis and Properties of Functional Organic Porous Materials

edited by

Hongpeng Li

and

Haibo Huang

submission deadline 30 Jun 2024 | 2 articles | Viewed by 3423

Keywords: porous material; zeolites; MOFs; COFs; HCPs; multi-functional application

(This special issue belongs to the Section Materials Chemistry)

Advances in Green Analytical Chemistry

edited by

Yu Yang

submission deadline 30 Jun 2024 | 3 articles | Viewed by 3247

Keywords: subcritical water; supercritical fluid; extraction; chromatography; organic solvent free; ethanol as eluent

(This special issue belongs to the Section Analytical Chemistry)

Advanced Chromatographic Methodologies for the Analysis of Natural and Bioactive Compounds

edited by

Zeineb Aturki

submission deadline 30 Jun 2024 | 3 articles | Viewed by 3170

Keywords: chromatographic methodologies; bioactive compounds; UPLC; capillary chromatography; nano-liquid chromatography; gas chromatography

(This special issue belongs to the Section Analytical Chemistry)

Antioxidant Activity of Natural Products: 2nd Edition

edited by

Zhiqiang Wang

and

Grażyna Zgórka

submission deadline 30 Jun 2024 | 2 articles | Viewed by 3113

Keywords: plant and dietary antioxidants; preparative-scale isolation; analytical methods; molecular mechanisms; antibiodegenerative potential in vitro and in vivo

(This special issue belongs to the Section Natural Products Chemistry)

Advances in Functional Organic Dye Chemistry

edited by

Agostina-Lina Capodilupo

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2938

Keywords: organic dyes; organic semiconductors; photonic organic crystals; organic emissive materials; organic electrochromic materials; organic electrofluorochromic materials; molecular sensors

(This special issue belongs to the Section Colorants)

Zn(II) and Cd(II) Coordination Polymers: Advances and Perspectives II

edited by

Marina Fonari

and

Rodica Olar

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2919

Keywords: new eco-friendly synthetic protocols; solution crystallization; solid-state grinding; solvent drop grinding; eco-friendly/new linkers; mixed-ligand; hybrid organic/inorganic ligand strategies; functionalized ligands; crystal engineering guidelines as a pathway for systematic design; SC-SC transformations in 1D; 2D; 3D CPs; adsorption/separation processes in 1D; 2D; CPs and 3D MOFs; flexibility; guest-responsive porous coordination networks; chiral coordination networks in the presence/absence of chiral components; the interplay of coordinative; hydrogen bonding; stacking interactions in sustaining crystal stability; the fluorescence properties of CPs; emission modulation; CPs as sensors for hazardous pollutants; rationales for effective multifunctional materials

(This special issue belongs to the Section Inorganic Chemistry)

Recent Advances in Raman Spectroscopy Analysis: Pharmaceutical and Biomedical Applications

edited by

Malvina Orkoula

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2854

Keywords: Raman microscopy and imaging; polymorphic forms in pharmacy; pharmaceutical finished products; cosmetics; biosimilars; stability of APIs and excipients; interaction between APIs and excipients; counterfeit identification; reverse engineering in pharmacy; tissue analysis; bone analysis; cartilage analysis; at-line; in-line

(This special issue belongs to the Section Analytical Chemistry)

Advances in Transition-Metal-Catalyzed Synthesis

edited by

Alexey G. Sergeev

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2782

Keywords: homogeneous catalysis; transition metals; organic synthesis; asymmetric synthesis; selectivity; C-C bond formation; C-X bond formation; C-H functionalisation; C-X functionalisation

(This special issue belongs to the Section Organic Chemistry)

Discovering New Drug Targets for Neurodegenerative Disorders

edited by

Halil İbrahim Ciftci

Belgin Sever

Flora Vidadi Hajiyeva

and

Mutlu Aytemir

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2774

Keywords: neurodegenerative disorders; Alzheimer’ s disease; Parkinson’ s disease; amyotrophic lateral sclerosis (ALS); specific enzyme regulation in neurodegenerative disorders; in silico approaches against neurodegenerative disorders; drug discovery in neurodegenerative disorders; determination of pharmacokinetic parameters in neurodegenerative disorders; targeted therapy for neurodegenerative disorders; current treatment strategies for neurodegenerative disorders

(This special issue belongs to the Section Medicinal Chemistry)

Functional Compounds from Microorganisms: Isolation, Characterization and Properties

edited by

Tzu-Ming Pan

and

Chun-Lin Lee

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2767

Keywords: bacteria; fungi; mold; virus; function; isolation; purification; identification

(This special issue belongs to the Section Natural Products Chemistry)

Exclusive Review Papers in ‘Inorganic Chemistry’—Are We Relevant?

edited by

Axel Klein

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2749

Keywords: energy conversion; sustainable chemistry; catalysis; medical chemistry; recycling; greener mineral processing; advanced materials

(This special issue belongs to the Section Inorganic Chemistry)

Phytochemical and Biological Activities of Natural Product with Application in Pharmacy and Food Technologies

edited by

and

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2688

Keywords: bioactive molecules; medical plants; antioxidant activity; bioactive compounds; food and pharmaceuticals application

(This special issue belongs to the Section Natural Products Chemistry)

Cyclization Reactions in Organic Synthesis: Recent Developments

edited by

Ana L. Cardoso

and

Maria Isabel L. Soares

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2677

Keywords: cyclization reactions; radical cyclization; cascade reaction; asymmetric cyclization; cycloaddition reactions; carbocyclic compounds; heterocyclic compounds; bioactive compounds

(This special issue belongs to the Section Organic Chemistry)

Physicochemical Research on Material Surfaces

edited by

Guiyong **ao

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2609

Keywords: coating; surface modification; micro/nano structure; chemical functionalization; biomaterials; bioactivity

(This special issue belongs to the Section Physical Chemistry)

Zeolite and Zeolite-Like Nanoparticles: Synthesis, Properties and Applications

edited by

Eng-Poh Ng

and

Ka-Lun Wong

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2449

Keywords: zeolite; metal organic framework; nanocrystals; green synthesis; advanced applications; functionalization

(This special issue belongs to the Section Materials Chemistry)

New Metal Catalysts for Sustainable Chemistry

edited by Wai Lun Man

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2411

Keywords: metal complexes; catalysis; mechanism; water splitting; CO2 reduction; C– H activation; O2 reduction; NH3 oxidation

(This special issue belongs to the Section Cross-Field Chemistry)

Metal-Based Nanomaterials in Catalysis and Electrochemistry

edited by Hongfei Cheng

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2322

Keywords: metal-based nanomaterials; material synthesis; reaction mechanism; catalysis; electrochemistry; energy applications

(This special issue belongs to the Section Materials Chemistry)

Applications of Nanoparticles in Catalysis, Sensing, and Biomedicine

edited by

Yu-Cheng Chang

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2232

Keywords: nanoparticles; nanocomposites; photocatalysis; electrochemical catalysis; chemical sensing; optical sensing; surface-ehanced Raman scatting; biomedicine

(This special issue belongs to the Section Nanochemistry)

Advances in Synthesis and Biological Activity of Novel Derivatives Based on Five-Membered Heterocyclic Scaffolds and Their Intermediates—Second Edition

edited by

Theodora Venera Apostol

George Mihai Nitulescu

and

Laura Ileana Socea

submission deadline 30 Jun 2024 | 3 articles | Viewed by 2217

Keywords: bioactive heterocycles; heterocyclic scaffolds; bioisosteric heterocyclic skeletons; azoles; pyrazole; oxazole; triazole; oxadiazole; drug design; in silico studies

(This special issue belongs to the Section Organic Chemistry)

Nanomaterials: Design and Applications

edited by

Tivadar Feczkó

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2083

Keywords: nanomaterials; nanostructured materials; nanocomposites; hybrid nanomaterials

(This special issue belongs to the Section Nanochemistry)

Chemistry of Lignin-Based Materials

edited by

Ana Lourenço

and

Jorge Gominho

submission deadline 30 Jun 2024 | 1 articles | Viewed by 2045

Keywords: lignin characteristics; separation methods; multi-analytical approach; lignin applications; biorefinery & zero-waste philosophy

(This special issue belongs to the Section Macromolecular Chemistry)

Recent Advances in Coordination Supramolecular Chemistry

edited by

Vicente Martí Centelles

and

Avijit Kumar Das

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2029

Keywords: supramolecular chemistry; self-assembly; metal– organic assemblies; molecular architectures; supramolecular materials; chemosensors; selective detection; colorimetric and fluorometric sensors

(This special issue belongs to the Section Organometallic Chemistry)

Advances in Antibacterial Molecules

edited by

Gildardo Rivera Sanchez

submission deadline 30 Jun 2024 | 2 articles | Viewed by 2024

Keywords: bacteria; drug design; drug repositioning; molecular docking; molecular dynamics; bioinformatics; synthesis; biomolecules; targets; in vitro assays; in vivo assays; small molecules; peptides; natural products; mechanism of action

(This special issue belongs to the Section Medicinal Chemistry)

Therapeutic and Nutraceutical Values of Functional Food

edited by

Sibao Chen

and

Guo-Qing Chen

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1923

Keywords: functional food; formulations; nutraceutical; natural compound; probiotic; biological activities; quality control; antioxidant

(This special issue belongs to the Section Natural Products Chemistry)

Natural and Un-Natural Peptides

edited by

Luca D. D'Andrea

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1906

Keywords: peptide chemistry; antimicrobial peptides; cell-penetrating peptides; peptides as drugs; peptides as diagnostics; peptide-based materials; bioactive peptides; antiviral peptides; anticancer peptides; immunogenic peptides; RiPPs; nonribosomal peptides

(This special issue belongs to the Section Bioorganic Chemistry)

Rare Earth Based Luminescent Materials

edited by

Joana Zaharieva

Dimitar Todorovsky

and

Maria Milanova

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1897

Keywords: lanthanides; rare earth; complexes; luminescence; inorganic materials; hybrid materials; composite materials; metal-organic frameworks; phosphors; sensors

(This special issue belongs to the Section Photochemistry)

Dopamine Receptors and Neurodegeneration

edited by

Marta Pardo

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1872

Keywords: dopamine; dopamine receptor; neurodegeneration; Alzheimer; Huntington; Parkinson

(This special issue belongs to the Section Medicinal Chemistry)

Spectroscopic Methods in Food Chemistry: From Milk and Dairy Products to Olive Oil

edited by

Constantinos G. Tsiafoulis

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1858

Keywords: food chemistry; analysis; -omics; milk; dairy products; food safety; bioactive compounds; olive oil; spectroscopy; NMR spectroscopy

(This special issue belongs to the Section Analytical Chemistry)

Advanced Synthetic Strategies in Nanomedicine and Its Impact on Biological and Medical Applications

edited by

Greish Khaled

and

Jun Fang

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1855

Keywords: novel applications of nanomedicine; theranostic applications; solid-state nanoparticles; vaccine development; immunotherapy; gene delivery; tissue engineering; cancer therapeutics

(This special issue belongs to the Section Nanochemistry)

Molecular Design and Theoretical Investigation of Energetic Materials

edited by

Fude Ren

Chao Chen

and

Nan Li

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1823

Keywords: molecule design of energetic material; contradiction between energy and sensitivity; DFT; molecular dynamics; statistical mechanics; machine learning; rare event method; high throughput in EMGI

(This special issue belongs to the Section Materials Chemistry)

Synthesis of Potential Bioactives

edited by

Bernhard Westermann

Hidayat Hussain

and

Oscar Endrigo Dorneles Rodrigues

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1681

Keywords: drug discovery; natural product derivatives; bioactive synthetic compounds; enzymatic synthesis; cancer; infectious diseases; microbial diseases; diabetes; cardiovascular diseases; human health; human diseases; computational methods; in vitro studies; in vivo studies; mechanism of action; target identification

(This special issue belongs to the Section Bioorganic Chemistry)

Peptides and Small Molecules as Anti-Cancer Agents II

edited by

Anna Lucia Tornesello

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1589

Keywords: peptides; peptide nucleic acid (PNA); theranostics; small molecules; nanoparticles; peptide drugs; lead compounds; peptidomimetics; synthetic anticancer peptides; cell-penetrating peptides; radiolabeled peptides; oncology

(This special issue belongs to the Section Medicinal Chemistry)

Porphyrin-Based Compounds: Synthesis and Application, 2nd Edition

edited by

Carlos Monteiro

M. Amparo F. Faustino

and

Carlos Serpa

submission deadline 30 Jun 2024 | 2 articles | Viewed by 1518

Keywords: synthesis of porphyrins and derivatives; functionalization/structural modification of porphyrinoids; structural and photophysical characterization; porphyrinic functional materials; biomedical applications optoelectronic applications; porphyrin– protein interactions

(This special issue belongs to the Section Organic Chemistry)

Advances in Molecular Dynamics and Molecular Modeling

edited by Franci Merzel

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1444

Keywords: MD simulations; advanced sampling techniques; multiscale modeling; principal component analysis

(This special issue belongs to the Section Computational and Theoretical Chemistry)

Natural Compounds Derived from Microorganisms: Development, Application and Challenge

edited by Ce Shi and Hongxun Tao

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1442

Keywords: microorganisms; metabolites; food and feeding industry; pharmacology; healthcare

(This special issue belongs to the Section Natural Products Chemistry)

Recent Advances in Organic Luminescent Materials

edited by

Dong Wang

and Fei Zhang

submission deadline 30 Jun 2024 | 1 articles | Viewed by 1439

Keywords: fluorescent probes; optical properties; bioluminescence; chemiluminescence; luminescence mechanism; biosensing; bioimaging; theranostics; medical application

(This special issue belongs to the Section Photochemistry)

Displaying special issue 51-100 on page 2 of 22.

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