Fluorine-Nitrogen-Codoped Carbon Dots as Fluorescent Switch Probes for Selective Fe(III) and Ascorbic Acid Sensing in Living Cells
Abstract
:1. Introduction
2. Experiment Section
2.1. Materials
2.2. Instruments
2.3. Synthesis of NFCDs and Measurement of Fluorescence Quantum Yield of NFCDs
2.4. Quantitative Detection of Fe3+ and AA
2.5. Cell Imaging and Cell Viability
3. Results and Discussion
3.1. Characterization of Nanoprobe NFCDs
3.2. Selectivity toward Fe3+ and AA
3.3. Detection Range and Limit of Fe3+ and AA for the NFCDs-Based Probe
3.4. Cell Imaging of NFCDs in Response to Fe3+ and AA
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
Sample Availability
References
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Types of Fluorescent Probes | Detection Range of Fe3+ (μM) | Detection Range of AA (μM) | Reference |
---|---|---|---|
Carbon dot | 0–0.38 | 0–0.78 | [32] |
Metal-organic framework | 5–60 | 1–20 | [11] |
Carbon dot | 0–145 | 0–150 | [33] |
nanoclusters | 0.5–80 | 0.2–80 | [34] |
Carbon dot | 0–100 | 0–100 | [35] |
Carbon dot | 0.75–125 | 0.25–30 | [36] |
Carbon dot | 0.2–150 | 10–80 | This work |
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Ye, S.; Zhang, M.; Guo, J.; Yu, X.; Song, J.; Zeng, P.; Qu, J.; Chen, Y.; Li, H. Fluorine-Nitrogen-Codoped Carbon Dots as Fluorescent Switch Probes for Selective Fe(III) and Ascorbic Acid Sensing in Living Cells. Molecules 2022, 27, 6158. https://doi.org/10.3390/molecules27196158
Ye S, Zhang M, Guo J, Yu X, Song J, Zeng P, Qu J, Chen Y, Li H. Fluorine-Nitrogen-Codoped Carbon Dots as Fluorescent Switch Probes for Selective Fe(III) and Ascorbic Acid Sensing in Living Cells. Molecules. 2022; 27(19):6158. https://doi.org/10.3390/molecules27196158
Chicago/Turabian StyleYe, Shuai, Mingming Zhang, Jiaqing Guo, **antong Yu, Jun Song, Pengju Zeng, Junle Qu, Yue Chen, and Hao Li. 2022. "Fluorine-Nitrogen-Codoped Carbon Dots as Fluorescent Switch Probes for Selective Fe(III) and Ascorbic Acid Sensing in Living Cells" Molecules 27, no. 19: 6158. https://doi.org/10.3390/molecules27196158