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Protein and Bioactive Peptides: Bioactivity, Applications and Health Benefits

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 384

Special Issue Editor


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Guest Editor
School of Human Nutrition, McGill University, Montreal, QC H9X 3V9, Canada
Interests: bioactive food compounds; protein hydrolysates; peptides; human digestion; gut microbiome; phytochemicals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Proteins and peptides play pivotal roles in various biological processes, serving as essential molecules in cellular signaling, enzymatic reactions and structural support.

This Special Issue aims to elucidate the intricate molecular mechanisms underlying the bioactivity of proteins and peptides, shedding light on their diverse functions and regulatory pathways. We welcome scholars to contribute original research articles and reviews that delve into the molecular basis of protein and peptide bioactivity, including their interactions with cellular receptors, signal transduction pathways and physiological effects.

Furthermore, this Special Issue highlights the wide-ranging applications of proteins and bioactive peptides in fields such as drug development, functional foods, nutraceuticals and biotechnology. By providing a comprehensive overview of the molecular biology aspects of proteins and peptides, this issue aims to facilitate advancements in understanding their health benefits and therapeutic potential. Join us in exploring the molecular intricacies of proteins and bioactive peptides and their implications for human health and disease.

Dr. Michele M. Iskandar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at mdpi.longhoe.net by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • protein
  • peptides
  • amino acids
  • composition
  • sequence
  • bioactivity
  • precursor protein

Published Papers (1 paper)

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Review

21 pages, 1192 KiB  
Review
Examining the Potential Applicability of Orexigenic and Anorexigenic Peptides in Veterinary Medicine for the Management of Obesity in Companion Animals
by Cezary Osiak-Wicha, Katarzyna Kras, Ewa Tomaszewska, Siemowit Muszyński and Marcin B. Arciszewski
Curr. Issues Mol. Biol. 2024, 46(7), 6725-6745; https://doi.org/10.3390/cimb46070401 - 1 Jul 2024
Viewed by 254
Abstract
This review article comprehensively explores the role of orexigenic and anorexigenic peptides in the management of obesity in companion animals, with a focus on clinical applications. Obesity in domestic animals, particularly dogs and cats, is prevalent, with significant implications for their health and [...] Read more.
This review article comprehensively explores the role of orexigenic and anorexigenic peptides in the management of obesity in companion animals, with a focus on clinical applications. Obesity in domestic animals, particularly dogs and cats, is prevalent, with significant implications for their health and well-being. Factors contributing to obesity include overfeeding, poor-quality diet, lack of physical activity, and genetic predispositions. Despite the seriousness of this condition, it is often underestimated, with societal perceptions sometimes reinforcing unhealthy behaviors. Understanding the regulation of food intake and identifying factors affecting the function of food intake-related proteins are crucial in combating obesity. Dysregulations in these proteins, whether due to genetic mutations, enzymatic dysfunctions, or receptor abnormalities, can have profound health consequences. Molecular biology techniques play a pivotal role in elucidating these mechanisms, offering insights into potential therapeutic interventions. The review categorizes food intake-related proteins into anorexigenic peptides (inhibitors of food intake) and orexigenic peptides (enhancers of food intake). It thoroughly examines current research on regulating energy balance in companion animals, emphasizing the clinical application of various peptides, including ghrelin, phoenixin (PNX), asprosin, glucagon-like peptide 1 (GLP-1), leptin, and nesfatin-1, in veterinary obesity management. This comprehensive review aims to provide valuable insights into the complex interplay between peptides, energy balance regulation, and obesity in companion animals. It underscores the importance of targeted interventions and highlights the potential of peptide-based therapies in improving the health outcomes of obese pets. Full article
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