Application of PET/CT in Diagnosis and Treatment of Cancers

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 300

Special Issue Editor


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Guest Editor
Nuclear Medicine Unit, Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, 15121 Alessandria, Italy
Interests: PET; PET/CT; prostate cancer; tumor

Special Issue Information

Dear Colleagues,

PET/CT technology is a medical imaging technique that combines positron emission tomography (PET) and computed tomography (CT) to simultaneously provide functional and anatomical information. It has significant application value in cancer diagnosis and treatment.

On one hand, PET/CT can accurately locate a tumor’s position, size, and metastasis. Because PET/CT can detect metabolic activity in tumors, it has high sensitivity and specificity for early-stage tumors that are difficult to detect using conventional imaging techniques, such as lung cancer and lymphoma. On the other hand, PET/CT plays an important role in evaluating the therapeutic effect of tumors and adjusting treatment plans. By comparing the results of PET/CT scans before and after treatment, doctors can determine whether the tumor has responded to treatment and whether the treatment plan needs to be adjusted. In addition, PET/CT can also be used to look for signs of tumor recurrence and monitor the patient's condition changes.

18F-FDG is the commonly used tracer for PET imaging and has a wide range of applications in the diagnosis of various tumors. Other innovative tracers, such as fibroblast activation protein inhibitor (FAPI) or prostate-specific membrane antigen (PSMA), labeled with Gallium-68 or Fluor-18, can be complementary with 18F-FDG or be very accurate alone in certain types of tumors. In this Special Issue, we hope to show the latest progress in the application of various tracers in tumor diagnosis and treatment. We look forward to your submissions and participation in this exciting Special Issue.

Dr. Alberto Miceli
Guest Editor

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Keywords

  • PET/CT
  • 18F-FDG
  • cancers
  • diagnosis
  • cancer treatment
 

Published Papers (1 paper)

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Research

15 pages, 5601 KiB  
Article
18F-FDG PET/CT- and MRI-Based Locally Advanced Cervical Cancer Early-Response Assessment after Concurrent Chemo- and Radiotherapy—Impact on Patient Outcomes and Survival Prediction
by Silvija Lucic, Milena Spirovski, Dragana Stojanovic, Andrea Peter, Jelena Licina, Olivera Ivanov, Natasa Milenovic and Milos A. Lucic
Diagnostics 2024, 14(13), 1432; https://doi.org/10.3390/diagnostics14131432 - 4 Jul 2024
Viewed by 167
Abstract
With one third of patients with locally advanced cervical cancer (LACC) expected to develop cancer recurrence in the first two years after therapy, accurate assessment of the response and timely detection of cancer recurrence after concurrent chemo- and radiotherapy (CCRT) treatment is of [...] Read more.
With one third of patients with locally advanced cervical cancer (LACC) expected to develop cancer recurrence in the first two years after therapy, accurate assessment of the response and timely detection of cancer recurrence after concurrent chemo- and radiotherapy (CCRT) treatment is of great importance. Although there is neither definite consensus about the preferred imaging modality, nor the time interval until the first diagnostic examination after CCRT, the National Comprehensive Cancer Network (NCCN) recommends the use of MRI and 18F-FDG PET/CT as a post-treatment LACC response-assessment imaging tools. In this study, we tried to appraise the early therapy response in LACC patients by both 18F-FDG PET/CT and MRI in regard to the follow-up imaging results and their mutual interrelationship, and to ascertain if the post-treatment 18F-FDG PET/CT and MRI results were related to the progression-free and overall survival rate in women with LACC after CCRT. We also aimed to estimate the early and follow-up diagnostic imaging impact on further therapy management. Based on our results, we concluded that 18F-FDG PET/CT did surpass MRI in the early assessment of therapeutic response in LACC patients after CCRT. Both modalities provided information that may serve as predictive biomarkers of outcome and LACC patients’ survival. Full article
(This article belongs to the Special Issue Application of PET/CT in Diagnosis and Treatment of Cancers)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

 
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