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Lipids and Cardiovascular Disease 2.0

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: closed (15 May 2024) | Viewed by 846

Special Issue Editors


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Guest Editor
LSU Health Sciences Center–Shreveport, Shreveport, LA 71103, USA
Interests: stroke; blood brain barrier; restenosis; oxidative stress; autotaxin; lysolipids
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
LSU Health Sciences Center–Shreveport, Shreveport, LA 71103, USA
Interests: vascular remodeling; stroke; alcohol abuse; myocardial injury; inflammation; lysolipids; drug discovery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is our pleasure to announce the launch of a new Special Issue in the IJMS journal focusing on lipids and cardiovascular disease. Despite advancements in the diagnosis and treatment of various stages of disease conditions, cardiovascular disease remains one of the most common leading causes of morbidity and mortality worldwide. An imbalance of the lipid microenvironment crucially contributes to atherosclerosis and is the major risk factor of the underlying cardiovascular disease. Dyslipidemia can lead to the deposition of lipid in the arterial intima, leading to inflammation and vascular remodeling, resulting in atherosclerotic plaque formation. Myocardial infarction and stroke are the lethal consequences of plaque rupture or erosion. Research and review articles on this broad and important topic are highly encouraged.

Dr. Manikandan Panchatcharam
Dr. Sumitra Miriyala
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at mdpi.longhoe.net by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • atherosclerosis
  • myocardial infarction
  • stroke
  • inflammation
  • vascular remodeling
  • lysolipids
  • cholesterols

Published Papers (1 paper)

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Review

27 pages, 2482 KiB  
Review
From Atherosclerotic Plaque to Myocardial Infarction—The Leading Cause of Coronary Artery Occlusion
by Ewelina Młynarska, Witold Czarnik, Piotr Fularski, Joanna Hajdys, Gabriela Majchrowicz, Magdalena Stabrawa, Jacek Rysz and Beata Franczyk
Int. J. Mol. Sci. 2024, 25(13), 7295; https://doi.org/10.3390/ijms25137295 - 2 Jul 2024
Viewed by 428
Abstract
Cardiovascular disease (CVD) constitutes the most common cause of death worldwide. In Europe alone, approximately 4 million people die annually due to CVD. The leading component of CVD leading to mortality is myocardial infarction (MI). MI is classified into several types. Type 1 [...] Read more.
Cardiovascular disease (CVD) constitutes the most common cause of death worldwide. In Europe alone, approximately 4 million people die annually due to CVD. The leading component of CVD leading to mortality is myocardial infarction (MI). MI is classified into several types. Type 1 is associated with atherosclerosis, type 2 results from inadequate oxygen supply to cardiomyocytes, type 3 is defined as sudden cardiac death, while types 4 and 5 are associated with procedures such as percutaneous coronary intervention and coronary artery bypass grafting, respectively. Of particular note is type 1, which is also the most frequently occurring form of MI. Factors predisposing to its occurrence include, among others, high levels of low-density lipoprotein cholesterol (LDL-C) in the blood, cigarette smoking, chronic kidney disease (CKD), diabetes mellitus (DM), hypertension, and familial hypercholesterolaemia (FH). The primary objective of this review is to elucidate the issues with regard to type 1 MI. Our paper delves into, amidst other aspects, its pathogenesis, risk assessment, diagnosis, pharmacotherapy, and interventional treatment options in both acute and long-term conditions. Full article
(This article belongs to the Special Issue Lipids and Cardiovascular Disease 2.0)
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