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Review Special Issue Series: Paradigm, Advances, and Future Directions in...
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Review Special Issue Series: Paradigm, Advances, and Future Directions in Oral Medicine

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1093

Special Issue Editor

Prof. Dr. Pia Lopez-Jornet

E-Mail Website
Guest Editor
Oral Medicine in the Department of Stomatology, Faculty of Dentistry, University of Murcia, 30008 Murcia, Spain
Interests: oral mucosa; oral lichen planus; leukoplakia; aphta; oral potentially malignant disorders (OPMDs); xerostomia; pain oral
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Advances in the field of oral medicine are remarkable. However, research is still needed in many areas of oral medicine, such as potentially malignant disorders, dermatologic diseases of the oral cavity and orofacial pain.

The development and advancement of diagnostic techniques, many of them minimally invasive, and treatments have led to improved diagnoses and quality of life.

In this Special Issue, we invite authors to present papers on clinical advances in oral medicine diagnostics and treatment.

Prof. Dr. Pia Lopez-Jornet
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at mdpi.longhoe.net by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • oral medicine
  • oral potentially malignant disorders
  • leukoplakia
  • oral lichen planus
  • orofacial pain
  • biopsy and liquid biopsy
  • biomarkers

Published Papers (1 paper)

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14 pages, 991 KiB  
Systematic Review
Effect of Photobiomodulation on Salivary Cytokines in Head and Neck Cancer Patients with Oral Mucositis: A Systematic Review
by Marwa Khalil, Omar Hamadah, Maher Saifo, Hasan Khalil, Mowaffak Adi, Faris Alabeedi and Omar Kujan
J. Clin. Med. 2024, 13(10), 2822; https://doi.org/10.3390/jcm13102822 - 10 May 2024
Viewed by 686
Abstract
Background: Oral mucositis is a common and distressing side effect of head and neck oncology treatment. Photobiomodulation therapy can be utilized to prevent and treat oral mucositis. Its impact on salivary cytokines has yet to be thoroughly investigated. This is the first systematic [...] Read more.
Background: Oral mucositis is a common and distressing side effect of head and neck oncology treatment. Photobiomodulation therapy can be utilized to prevent and treat oral mucositis. Its impact on salivary cytokines has yet to be thoroughly investigated. This is the first systematic review aiming to evaluate the effect of photobiomodulation on salivary cytokines in patients undergoing anticancer treatment. Methods: Numerous data resources, from the Web of Science, Embase, ScienceDirect, PubMed, Cochrane Library, and Scopus were sought. Articles published up until February 2024 were included if they met the following inclusion criteria: clinical trials reporting the effect on salivary cytokines in patients undergoing anticancer therapy. The methodological quality was assessed using several appraisal tools. Results: Four studies were deemed eligible for inclusion. All the studies were conducted in Brazil and used an InGaAlP diode laser with a wavelength of 660 nm. The included studies had a relatively low risk of bias. The head and neck cancer patients’ salivary cytokines that were assessed by the studies, along with photobiomodulation therapy, included IL-12p70, TNF-α, IL-6, IL-8, IL-10, CXCL8, and IL-1β. The results varied among the studies. Conclusions: Our results show that photobiomodulation demonstrated positive results for reducing the severity of OM in all the included studies. Among the examined salivary cytokines, IL-6 is the most relevant cytokine for oral mucositis development and severity. A variation in the cytokine levels between the studies was noted due to differences in the type of anticancer treatment and saliva sampling. Full article
(This article belongs to the Special Issue Review Special Issue Series: Paradigm, Advances, and Future Directions in Oral Medicine)
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