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Synthesis of Nanomaterials and Their Applications in Biomedicine
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Synthesis of Nanomaterials and Their Applications in Biomedicine

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Materials Chemistry".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1126

Special Issue Editor

Dr. Nefeli Lagopati

E-Mail Website
Guest Editor
Department of Medicine, School of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece
Interests: nanomedicine; nanotechnology; biomaterials; cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Advances in nanoscience have been greatly beneficial to biomedicine with regard to the preparation of innovative nanomaterials, hybrid nanocomposites, multifunctional materials, and 3D-printed structures enhanced with nanoparticles, either for diagnosis or therapeutic approaches.

This Special Issue is concerned with the synthesis of nanomaterials and their applications in biomedicine, including the development of organic and inorganic nanomaterials with the potential to be used for biomedical applications. Thus, topics for this Special Issue may include synthesis procedures, physicochemical characterization, and interactions of various nanomaterials with biological systems. Special attention will be given to photodynamic and photothermal applications, theranostic approaches, and bioimaging.

Both original manuscripts and reviews are welcome.

Dr. Nefeli Lagopati
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at mdpi.longhoe.net by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanomaterials
  • biomaterials
  • synthesis
  • characterization
  • diagnosis
  • treatment
  • cytotoxicity
  • biocompatibility

Published Papers (2 papers)

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Research

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17 pages, 6837 KiB  
Article
Synergistic Therapeutic Effects of D-Mannitol–Cerium–Quercetin (Rutin) Coordination Polymer Nanoparticles on Acute Lung Injury
by Yusheng Zhang, Hong Wang, Ruiying Yang, Ying Zhang, Yao Chen, Cui** Jiang and **anyu Li
Molecules 2024, 29(12), 2819; https://doi.org/10.3390/molecules29122819 - 13 Jun 2024
Viewed by 459
Abstract
Acute lung injury (ALI) remains a significant global health issue, necessitating novel therapeutic interventions. In our latest study, we pioneered the use of D-mannitol–cerium–quercetin/rutin coordination polymer nanoparticles (MCQ/R NPs) as a potential treatment for ALI. The MCQ/R NPs, which integrate rutin and quercetin [...] Read more.
Acute lung injury (ALI) remains a significant global health issue, necessitating novel therapeutic interventions. In our latest study, we pioneered the use of D-mannitol–cerium–quercetin/rutin coordination polymer nanoparticles (MCQ/R NPs) as a potential treatment for ALI. The MCQ/R NPs, which integrate rutin and quercetin for their therapeutic potential and D-mannitol for its pulmonary targeting, displayed exceptional efficacy. By utilizing cerium ions for optimal nanoparticle assembly, the MCQ/R NPs demonstrated an average size of less than 160 nm. Impressively, these nanoparticles outperformed conventional treatments in both antioxidative capabilities and biocompatibility. Moreover, our in vivo studies on LPS-induced ALI mice showed a significant reduction in lung tissue inflammation. This groundbreaking research presents MCQ/R NPs as a promising new approach in ALI therapeutics. Full article
(This article belongs to the Special Issue Synthesis of Nanomaterials and Their Applications in Biomedicine)
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Review

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29 pages, 664 KiB  
Review
Nano-Based Approaches in Surface Modifications of Dental Implants: A Literature Review
by Chrysa Marasli, Hector Katifelis, Maria Gazouli and Nefeli Lagopati
Molecules 2024, 29(13), 3061; https://doi.org/10.3390/molecules29133061 - 27 Jun 2024
Viewed by 500
Abstract
Rehabilitation of fully or partially edentulous patients with dental implants represents one of the most frequently used surgical procedures. The work of Branemark, who observed that a piece of titanium embedded in rabbit bone became firmly attached and difficult to remove, introduced the [...] Read more.
Rehabilitation of fully or partially edentulous patients with dental implants represents one of the most frequently used surgical procedures. The work of Branemark, who observed that a piece of titanium embedded in rabbit bone became firmly attached and difficult to remove, introduced the concept of osseointegration and revolutionized modern dentistry. Since then, an ever-growing need for improved implant materials towards enhanced material–tissue integration has emerged. There is a strong belief that nanoscale materials will produce a superior generation of implants with high efficiency, low cost, and high volume. The aim of this review is to explore the contribution of nanomaterials in implantology. A variety of nanomaterials have been proposed as potential candidates for implant surface customization. They can have inherent antibacterial properties, provide enhanced conditions for osseointegration, or act as reservoirs for biomolecules and drugs. Titania nanotubes alone or in combination with biological agents or drugs are used for enhanced tissue integration in dental implants. Regarding immunomodulation and in order to avoid implant rejection, titania nanotubes, graphene, and biopolymers have successfully been utilized, sometimes loaded with anti-inflammatory agents and extracellular vesicles. Peri-implantitis prevention can be achieved through the inherent antibacterial properties of metal nanoparticles and chitosan or hybrid coatings bearing antibiotic substances. For improved corrosion resistance various materials have been explored. However, even though these modifications have shown promising results, future research is necessary to assess their clinical behavior in humans and proceed to widespread commercialization. Full article
(This article belongs to the Special Issue Synthesis of Nanomaterials and Their Applications in Biomedicine)
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