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Research and Application of Plant Sourced Polysaccharides—2nd Edition
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Research and Application of Plant Sourced Polysaccharides—2nd Edition

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 933

Special Issue Editors

Dr. **aolong Ji

E-Mail Website
Guest Editor
College of Food and Bioengineering, Zhengzhou University of Light Industry, Zhengzhou 450001, China
Interests: polysaccharide; starch; jujube; NMR; polymer
Special Issues, Collections and Topics in MDPI journals
Dr. **n Wang

E-Mail Website
Guest Editor
College of Food Science and Engineering, Northwest A&F University, **anyang, China
Interests: polysaccharide; structure; anti-inflammatory; immunologic activity
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Polysaccharides are the most abundant and diverse class of organic compounds occurring in nature. They can be found in almost all plants and are also one of the most versatile materials available, and, therefore, have played a critical role in the development of new products, ranging from foods, nutraceuticals, cosmetics, and so on.

In recent years, with the increased attention paid to the study of natural polysaccharides, there have been significant developments in our knowledge of polysaccharides in each related aspect, which also promoted the exploitation of natural plant polysaccharides in the food and pharmaceutical industries, among others. Therefore, the purpose of this Special Issue is to cover a broad spectrum of original research and reviews contributions on natural plant polysaccharides.

We invite authors to contribute original research articles, as well as review articles, about the advances in the study and exploitation of natural plant polysaccharides, which have current or potential applications in areas such as functional foods, nutraceuticals, and pharmaceuticals.

Potential topics include, but are not limited to:

  • Novel chemical, enzymatic, and physical extraction techniques for natural plant polysaccharide preparation;
  • Physicochemical characterization and biological effects of plant polysaccharides;
  • Structural analysis and modification of plant polysaccharides;
  • Recent developments in the analytical methodologies of plant polysaccharides;
  • Study on the functional activity mechanism of plant polysaccharides;
  • Application of nature plant polysaccharides to foods, nutraceuticals, pharmaceuticals, cosmetics, or other products.
  • Any other topics that are deemed relevant to the main scope of this Special Issue.

Dr. **aolong Ji
Dr. **n Wang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at mdpi.longhoe.net by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polysaccharide
  • characterization
  • structure
  • physiochemical properties
  • functional activity

Published Papers (2 papers)

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Research

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23 pages, 10067 KiB  
Article
The Isolation, Structural Characterization and Anti-Inflammatory Potentials of Neutral Polysaccharides from the Roots of Isatis indigotica Fort.
by Yu Shen, Shihao Wu, Mingming Song, Huiming Zhang, Hong Zhao, Lili Wu, Hongbo Zhao, Hongbin Qiu and Yu Zhang
Molecules 2024, 29(11), 2683; https://doi.org/10.3390/molecules29112683 - 5 Jun 2024
Viewed by 410
Abstract
Polysaccharides have been assessed as a potential natural active component in Chinese herbal medicine with anti-inflammatory properties. However, the complex and indefinite structures of polysaccharides limit their applications. This study explains the structures and anti-inflammatory potentials of three neutral polysaccharides, RIP-A1 (Mw [...] Read more.
Polysaccharides have been assessed as a potential natural active component in Chinese herbal medicine with anti-inflammatory properties. However, the complex and indefinite structures of polysaccharides limit their applications. This study explains the structures and anti-inflammatory potentials of three neutral polysaccharides, RIP-A1 (Mw 1.8 × 104 Da), RIP-B1 (Mw 7.4 × 104 Da) and RIP-B2 (Mw 9.3 × 104 Da), which were isolated from the roots of Isatis indigotica Fort. with sequenced ultrafiltration membrane columns, DEAE-52 and Sephadex G-100. The planar structures and microstructures of RIP-A1, RIP-B1 and RIP-B2 were further determined by HPGPC, GC–MS, methylation analysis, FT-IR, SEM and AFM, in which the structure of RIP-A1 was elucidated in detail using 1D/2D NMR. The Raw 264.7 cells were used for the anti-inflammatory activity in vitro. The results showed that RIP-A1, RIP-B1 and RIP-B2 are all neutral polysaccharides, with RIP-A1 having the smallest Mw and the simplest monosaccharide composition of the three. RIP-A1 is mainly composed of Ara and Gal, except for a small quantity of Rha. Its main structure is covered with glycosidic linkages of T-α-Araf, 1,2-α-Rhap, 1,5-α-Araf, T-β-Galp, 1,2,4-α-Rhap, 1,3,5-α-Araf and 1,6-β-Galp with 0.33:0.12:1.02:0.09:0.45:11.41:10.23. RIP-A1 significantly inhibited pro-inflammatory cytokines (NO, TNF-α, IL-6 and IL-1β) and increased anti-inflammatory cytokines (IL-4) in LPS-stimulated RAW 264.7 cells. Moreover, RIP-A1 could significantly inhibit the mRNA expression of TNF-α, IL-6 and L-1β. It could also activate IKK, p65 and IκBα (the components of the NF-κB signaling pathway). In conclusion, the above results show the structural characterization and anti-inflammatory potentials of RIP-A1 as an effective natural anti-inflammatory drug. Full article
(This article belongs to the Special Issue Research and Application of Plant Sourced Polysaccharides—2nd Edition)
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Review

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18 pages, 3541 KiB  
Review
Recent Advances in Polysaccharides from Chaenomeles speciosa (Sweet) Nakai.: Extraction, Purification, Structural Characteristics, Health Benefits, and Applications
by Aiqi Yu, Wen**g Hu, Haizheng Bi, Lei Fu, Zhibin Wang, Meng Wang and Haixue Kuang
Molecules 2024, 29(13), 2984; https://doi.org/10.3390/molecules29132984 - 23 Jun 2024
Viewed by 283
Abstract
This article systematically reviews the extraction and purification methods, structural characteristics, structure–activity relationship, and health benefits of C. speciosa polysaccharides, and their potential application in food, medicine, functional products, and feed, in order to provide a useful reference for future research. Chaenomeles speciosa [...] Read more.
This article systematically reviews the extraction and purification methods, structural characteristics, structure–activity relationship, and health benefits of C. speciosa polysaccharides, and their potential application in food, medicine, functional products, and feed, in order to provide a useful reference for future research. Chaenomeles speciosa (Sweet) Nakai. has attracted the attention of health consumers and medical researchers as a traditional Chinese medicine with edible, medicinal, and nutritional benefits. According to this study, C. speciosa polysaccharides have significant health benefits, such as anti-diaetic, anti-inflammatory and analgesic, anti-tumor, and immunomodulatory effects. Researchers determined the molecular weight, structural characteristics, and monosaccharide composition and ratio of C. speciosa polysaccharides by water extraction and alcohol precipitation. This study will lay a solid foundation for further optimization of the extraction process of C. speciosa polysaccharides and the development of their products. As an active ingredient with high value, C. speciosa polysaccharides are worthy of further study and full development. C. speciosa polysaccharides should be further explored in the future, to innovate their extraction methods, enrich their types and biological activities, and lay a solid foundation for further research and development of products containing polysaccharides that are beneficial to the human body. Full article
(This article belongs to the Special Issue Research and Application of Plant Sourced Polysaccharides—2nd Edition)
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