Parasites and Parasitic Diseases in the Livestock Industry in Latin America

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 1248

Special Issue Editor


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Guest Editor
Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, Jiutepec 62550, Morelos, Mexico
Interests: ecto-parasites; endo-parasites; control strategies; sustainability; ruminants
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Special Issue Information

Dear Colleagues,

From the point of view of biodiversity, Latin America (LA) is a privileged region, since it contains a large variety of plants, animals, and forms of life. It is estimated that more than 40% of the world's biodiversity is situated in this area. This region accounts for around sixty percent of global terrestrial life, and diverse freshwater and marine species can be found within this region. The bio-diversity in this region where organisms share the same habitats trying to survive in the face of adverse biotic and abiotic conditions promotes the establishment of natural regulating mechanisms such as parasitism. Cattle and small ruminants are continuously exposed to external parasites, i.e., ticks (Rhipicephalus microplus), horn flies (Haematobia irritans) and stable flies(Stomoxis calcitrans), and also to internal parasitosis, including gastrointestinal parasitic nematodes, liver fluke Fasciola hepatica and protozoa, i.e., Eimeria spp. These parasitosis are responsible for important economic loses affecting the livestock industry. The problem caused by parasites to animals worsens by the lack of efficacy of anti-parasitic chemical drugs due to the development of anti-parasitic resistance (APR). The effects and consequences of parasitic diseases together with other infectious diseases on animal health and the economy of farmers demotivate them and sometimes, producers abandon their livestock activity. The present Special Issue displays research studies developed in the LA region that contribute to understanding the problem of ecto and endo parasites in cattle and small ruminants from an epidemiological perspective, including the problem of APR and sustainable methods of control and prevention of the main parasitic diseases affecting ruminants in LA.    

Topics for submissions

  • Epidemiology of ecto and endo parasitic diseases;
  • Resistance to anthelmintic chemical drugs;
  • Resistance to ixodicides;
  • Plant and plant metabolites against ecto and endo parasites;
  • Biological control of ecto and endo parasites;
  • Other sustainable alternative methods of control of ecto and endo parasitic diseases

Dr. Pedro Mendoza de Gives
Guest Editor

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Keywords

  • parasitic diseases
  • epidemiology
  • antiparasitic resistance
  • alternative methods of control
  • livestock
  • small ruminants

Published Papers (2 papers)

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Research

12 pages, 830 KiB  
Article
Understanding Artemisia cina Ethyl Acetate Extract’s Anthelmintic Effect on Haemonchus contortus Eggs and L3 Larvae: The Synergism of Peruvin Binary Mixtures
by Luis David Arango-De-la Pava, Manasés González-Cortazar, Alejandro Zamilpa, Jorge Alfredo Cuéllar-Ordaz, Héctor Alejandro de la Cruz-Cruz, Rosa Isabel Higuera-Piedrahita and Raquel López-Arellano
Pathogens 2024, 13(6), 509; https://doi.org/10.3390/pathogens13060509 - 16 Jun 2024
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Abstract
Haemonchus contortus, a blood-feeding parasite in grazing sheep, causes economic losses. Drug resistance necessitates exploring plant-based anthelmintics like Artemisia cina (Asteraceae). The plant, particularly its ethyl acetate extract, shows anthelmintic activity against H. contortus. However, there is limited information on pharmacodynamic [...] Read more.
Haemonchus contortus, a blood-feeding parasite in grazing sheep, causes economic losses. Drug resistance necessitates exploring plant-based anthelmintics like Artemisia cina (Asteraceae). The plant, particularly its ethyl acetate extract, shows anthelmintic activity against H. contortus. However, there is limited information on pharmacodynamic interactions in ethyl acetate compounds. The study aims to identify pharmacodynamic interactions in the ethyl acetate extract of A. cina with anthelmintic effects on H. contortus eggs and L3 larvae using binary mixtures. Bioactive compounds were isolated via chromatography and identified using spectroscopic techniques. Pharmacodynamic interactions were assessed through binary mixtures with a main compound. Four bioactive compounds were identified: 1-nonacosanol, hentriacontane, peruvin, and cinic acid. Binary mixtures, with peruvin as the main compound, were performed. Peruvin/1-nonacosanol-hentriacontane and peruvin/cinic acid mixtures demonstrated 1.42-fold and 4.87-fold increased lethal effects in H. contortus L3 infective larvae, respectively, at a 0.50LC25/0.50LC25 concentration. In this work, we determined the synergism between bioactive compounds isolated from the ethyl acetate extract of A. cina and identified unreported compounds for the specie. Full article
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18 pages, 4633 KiB  
Article
Assessing the In Vitro Individual and Combined Effect of Arthrobotrys oligospora and A. musiformis (Orbiliales) Liquid Culture Filtrates against Infective Larvae of the Sheep Blood-Feeding Nematode Haemonchus contortus (Trichostrongylidae)
by Antonio Colinas-Picazo, Pedro Mendoza-de Gives, Gustavo Pérez-Anzúrez, Enrique Gutiérrez-Medina, Génesis Andrea Bautista-García, Edgar Jesús Delgado-Núñez and Agustín Olmedo-Juárez
Pathogens 2024, 13(6), 498; https://doi.org/10.3390/pathogens13060498 - 11 Jun 2024
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Abstract
Background: Arthrobotrys species are nematophagous fungi that secrete extracellular nematocidal products (ECP). The individual and combined effects of ECP from Arthrobotrys oligospora (Ao) and A. musiformis (Am) growth in liquid media against Haemonchus contortus L3 (HcL3) were assessed. Methods: [...] Read more.
Background: Arthrobotrys species are nematophagous fungi that secrete extracellular nematocidal products (ECP). The individual and combined effects of ECP from Arthrobotrys oligospora (Ao) and A. musiformis (Am) growth in liquid media against Haemonchus contortus L3 (HcL3) were assessed. Methods: The isolation, morphological (MI) and molecular identification (Mol-I), assessment of nematocidal activity (NA) of fungal liquid culture filtrates (LCF) in two liquid media alone and in combination and the myco-compound profile identification (MCP) were performed. Results: The MI suggested that the fungi corresponded to the species Ao and Am. This result was confirmed by PCR analysis followed by sequencing, alignment and a phylogenetic analysis. Likewise, the highest Hc mortalities were 91.4% with individual LCF of Am and 86.2% with those of Ao at the highest concentration (100 mg/mL) in Czapek-Dox Broth. The combination of both LCF resulted in a similarly high larval mortality with no statistical differences in relation to individual activity (p > 0.05). The MCP showed the presence of alkaloids in both fungi. Coumarins, sterols and saponins were found only in Ao. Main conclusions: Both fungi produced ECP with a high NA that could be identified and assessed in future studies as potential natural anthelmintic compounds. Full article
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