Antibiotic Misuse during the COVID-19 Pandemic in Lebanon: A Cross-Sectional Study
Abstract
:1. Introduction
2. Methods
2.1. Study Design and Participants
2.2. Instrument
2.3. Ethical Considerations
2.4. Statistical Analysis
3. Results
3.1. Socio-Demographic Characteristics
3.2. COVID-19 Infection
3.3. Determinants of Antibiotic Misuse
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
- Chen, N.; Zhou, M.; Dong, X.; Qu, J.; Gong, F.; Han, Y.; Qiu, Y.; Wang, J.; Liu, Y.; Wei, Y.; et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet 2020, 395, 507–513. [Google Scholar] [CrossRef] [PubMed]
- Huang, C.; Wang, Y.; Li, X.; Ren, L.; Zhao, J.; Hu, Y.; Zhang, L.; Fan, G.; Xu, J.; Gu, X.; et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020, 395, 497–506. [Google Scholar] [CrossRef] [PubMed]
- Noureddine, F.Y.; Chakkour, M.; El Roz, A.; Reda, J.; Al Sahily, R.; Assi, A.; Joma, M.; Salami, H.; Hashem, S.J.; Harb, B.; et al. The Emergence of SARS-CoV-2 Variant(s) and Its Impact on the Prevalence of COVID-19 Cases in the Nabatieh Region, Lebanon. Clin. Chim. Acta 2024, 558, 119368. [Google Scholar] [CrossRef]
- Zhou, F.; Yu, T.; Du, R.; Fan, G.; Liu, Y.; Liu, Z.; ** countries. Part I: Recent trends and current status. Lancet Infect. Dis. 2005, 5, 481–493. [Google Scholar] [CrossRef] [PubMed]
- Cho, H.-J.; Hong, S.-J.; Park, S. Knowledge and beliefs of primary care physicians, pharmacists, and parents on antibiotic use for the pediatric common cold. Soc. Sci. Med. 2004, 58, 623–629. [Google Scholar] [CrossRef] [PubMed]
- Kardas, P.; Devine, S.; Golembesky, A. A systematic review and meta-analysis of misuse of antibiotic therapies in the community. Int. J. Antimicrob. Agents 2005, 26, 106–113. [Google Scholar] [CrossRef]
- Peng, D.; Wang, X.; Xu, Y.; Sun, C.; Zhou, X. Antibiotic misuse among university students in developed and less developed regions of China: A cross-sectional survey. Glob. Health Action 2018, 11, 1496973. [Google Scholar] [CrossRef]
Variables | Classification | Frequency (N) | Percentage (%) |
---|---|---|---|
Gender | Male Female | 135 343 | 28.2 71.8 |
Diploma | University degree Higher technical | 401 43 | 83.9 10.3 |
Working field | Health sector | 242 | 50.6 |
Monthly income | <10,000,000 10,000,000–20,000,000 >20,000,000 | 314 66 98 | 65.7 13.8 20.5 |
Physical activities | Inactive (no physical activity) Moderately to very active (equal or more than two hours per week) | 193 285 | 40.4 59.6 |
Smoking | Yes No | 184 294 | 38.5 61.5 |
BMI | Mean ± SD Underweight (BMI < 18.5) Normal weight (BMI = 18.5 < 25) Overweight (BMI = 25 < 30) obese (BMI > 30) | 24.4 ± 5 33 262 129 54 | 6.9 54.8 27 11.3 |
Chronic diseases | Cardiovascular diseases Pulmonary diseases (BPCO, Asthma) Diabetes Others | 16 13 03 12 | 36.4 29.5 6.8 27.3 |
Variables | Classification | Frequency (N) | Percentage (%) |
---|---|---|---|
COVID-19 vaccine | Yes No One dose Two doses Three doses | 384 94 22 270 92 | 80.3 19.7 5.7 70.3 23.9 |
Perception of COVID-19 infection’s severity | Mild Moderate Severe | 135 240 103 | 28.2 50.2 21.5 |
Doctor’s consultation | Yes No | 150 328 | 31.4 68.6 |
Hospital admission | Yes No | 37 441 | 7.7 92.3 |
Antibiotic treatment | Yes No One antibiotic Two antibiotics | 192 286 146 46 | 40.2 59.8 76.1 23.9 |
Name of antibiotic | Azithromycin Augmentin Tavanic Don’t remember | 37 22 12 121 | 19.3 11.5 6.2 63 |
Prescription of antibiotic | Physician Pharmacist Self-taken Others (family, friends…) | 98 45 28 21 | 51 23.4 14.5 10.9 |
Rationale for using antibiotics | To lessen symptoms As a preventative measure | 143 49 | 74.5 25.5 |
Symptoms as rationale for taking antibiotics | Fever Difficulty in breathing Chest pain Others: headache, muscle pain, back pain… | 96 28 23 45 | 50 14.6 12 23.4 |
Respect the antibiotic therapy’s role | Respect antibiotic therapy’s role Discontinued the antibiotic treatment when felt better | 114 78 | 59.3 40.6 |
Antibiotic Use | p-Value | |||
---|---|---|---|---|
Yes | No | |||
COVID-19 vaccine | Yes No | 146 46 | 238 48 | 0.053 |
Smoking | Yes No | 90 102 | 94 192 | 0.002 * |
Perception of COVID-19 infection’s severity | Mild to Moderate Severe | 134 58 | 241 45 | 0.000 * |
Work in health sector | Yes No | 90 102 | 152 134 | 0.179 |
Education level | University Level Others | 155 37 | 246 40 | 0.123 |
Severity of COVID-19 | Perception of COVID-19 Infection’s Severity | p-Value | ||
---|---|---|---|---|
Mild to Moderate | Severe | |||
Gender | Male Female | 114 261 | 21 82 | 0.046 |
Smoking | Yes No | 130 245 | 54 49 | 0.001 * |
Hospital admission | Yes No | 15 360 | 22 81 | 0.000 * |
Nonprescription Antibiotic Use | Respecting Antibiotic Therapy’s Role | ||||||
---|---|---|---|---|---|---|---|
Physician Prescription ATB Use | Nonprescription ATB Use | p-Value | Yes | No | p-Value | ||
Gender | Male Female | 26 72 | 28 66 | 0.616 | 21 55 | 33 83 | 0.902 |
Education Level | University Level Others | 85 13 | 70 24 | 0.031 * | 61 15 | 94 22 | 0.895 |
Working field: Health Sector | Yes No | 56 42 | 34 60 | 0.004 * | 24 52 | 66 50 | 0.001 * |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Chaaban, T.; Ezzeddine, Z.; Ghssein, G. Antibiotic Misuse during the COVID-19 Pandemic in Lebanon: A Cross-Sectional Study. COVID 2024, 4, 921-929. https://doi.org/10.3390/covid4070064
Chaaban T, Ezzeddine Z, Ghssein G. Antibiotic Misuse during the COVID-19 Pandemic in Lebanon: A Cross-Sectional Study. COVID. 2024; 4(7):921-929. https://doi.org/10.3390/covid4070064
Chicago/Turabian StyleChaaban, Taghrid, Zeinab Ezzeddine, and Ghassan Ghssein. 2024. "Antibiotic Misuse during the COVID-19 Pandemic in Lebanon: A Cross-Sectional Study" COVID 4, no. 7: 921-929. https://doi.org/10.3390/covid4070064